CDC42SE1

Gene Symbol CDC42SE1
Entrez Gene 56882
Alt Symbol SCIP1, SPEC1
Species Human
Gene Type protein-coding
Description CDC42 small effector 1
Other Description 1300002M12Rik|CDC42 small effector protein 1|CDC42-binding protein SCIP1|signaling molecule SPEC1 beta|small effector of CDC42 protein 1|small protein effector 1 of Cdc42
Swissprots Q9NRR8 Q9NQR2 Q9HB17 D3DV12
Accessions EAW53477 EAW53478 EAW53479 Q9NRR8 AF187845 AAF87597 AF286041 AAF97248 AF286592 AAG17723 AK054914 BC012796 AAH12796 BC041604 AAH41604 BP340339 BX339337 DQ894194 ABM85120 NM_001038707 NP_001033796 NM_020239 NP_064624
Function Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583, ECO:0000269|PubMed:17045588}.
Subcellular Location Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Recruited to the activated TCR prior actin polymerization.
Tissue Specificity Widely expressed. Expressed at higher level in T-lymphocytes, dendritic and whole blood cells. {ECO:0000269|PubMed:15840583}.

CDC42SE1-Over-expression-Lysate - LY14200a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag CDC42SE1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDC42SE1 gene.

CDC42SE1 overexpression lysate - LY422010 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CDC42SE1 overexpression lysate - LY425627 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

CDC42SE1 293 Cell Lysate - 406157 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

CDC42SE1 Overexpression Lysate (Native) - NBL1-09011 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CDC42SE1 Overexpression Lysate (Adult Normal) [NBL1-09011] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDC42SE1.

CDC42SE1 Overexpression Lysate (Native) - NBP2-08563 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: CDC42SE1 Overexpression Lysate (Adult Normal) [NBP2-08563] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CDC42SE1.

CDC42SE1 Overexpression Lysate (Native) - NBP2-09200 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

CDC42SE1 Over-expression Lysate Product - GWB-C862EA from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human CDC42SE1 Knockdown Stable Cell Line - CSC-DC002814 from Creative biogene

Category Cell Line
Species Human
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