CDC42SE1

Gene Symbol CDC42SE1
Entrez Gene 56882
Alt Symbol SCIP1, SPEC1
Species Human
Gene Type protein-coding
Description CDC42 small effector 1
Other Description 1300002M12Rik|CDC42 small effector protein 1|CDC42-binding protein SCIP1|signaling molecule SPEC1 beta|small effector of CDC42 protein 1|small protein effector 1 of Cdc42
Swissprots Q9NRR8 Q9NQR2 Q9HB17 D3DV12
Accessions EAW53477 EAW53478 EAW53479 Q9NRR8 AF187845 AAF87597 AF286041 AAF97248 AF286592 AAG17723 AK054914 BC012796 AAH12796 BC041604 AAH41604 BP340339 BX339337 DQ894194 ABM85120 NM_001038707 NP_001033796 NM_020239 NP_064624
Function Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583, ECO:0000269|PubMed:17045588}.
Subcellular Location Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Recruited to the activated TCR prior actin polymerization.
Tissue Specificity Widely expressed. Expressed at higher level in T-lymphocytes, dendritic and whole blood cells. {ECO:0000269|PubMed:15840583}.

SPEC1 CRISPR/Cas9 KO Plasmid (h) - sc-410599 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 HDR Plasmid (h) - sc-410599-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 Double Nickase Plasmid (h) - sc-410599-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 Double Nickase Plasmid (h2) - sc-410599-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 CRISPR Activation Plasmid (h) - sc-410599-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 CRISPR Activation Plasmid (h2) - sc-410599-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 Lentiviral Activation Particles (h) - sc-410599-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 Lentiviral Activation Particles (h2) - sc-410599-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SPEC1 siRNA (h) - sc-78876 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPEC1 shRNA Plasmid (h) - sc-78876-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SPEC1 shRNA (h) Lentiviral Particles - sc-78876-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU067651 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN5791 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5791 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11355 from Sigma-Aldrich

Category miRNA

CDC42SE1 siRNA (Human) - CRJ1191 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDC42SE1 - MBS8225609 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CDC42SE1 (NM_020239.3) - SHH259917 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CDC42SE1(NM_001038707.1) - SHG161817 from Creative biogene

Category siRNA
Species Reactivities Human

Human CDC42SE1 siRNA - orb271692 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CDC42SE1 shRNA Plasmid (Human) - CHJ1191 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CDC42SE1 miRNA 3'UTR clone - MiUTR1H-01961 from Creative biogene

Species Reactivities Human

CDC42SE1 miRNA 3'UTR clone - MiUTR4H-TG01908 from Creative biogene

Species Reactivities Human
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