Gene Symbol | CDC42SE1 |
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Entrez Gene | 56882 |
Alt Symbol | SCIP1, SPEC1 |
Species | Human |
Gene Type | protein-coding |
Description | CDC42 small effector 1 |
Other Description | 1300002M12Rik|CDC42 small effector protein 1|CDC42-binding protein SCIP1|signaling molecule SPEC1 beta|small effector of CDC42 protein 1|small protein effector 1 of Cdc42 |
Swissprots | Q9NRR8 Q9NQR2 Q9HB17 D3DV12 |
Accessions | EAW53477 EAW53478 EAW53479 Q9NRR8 AF187845 AAF87597 AF286041 AAF97248 AF286592 AAG17723 AK054914 BC012796 AAH12796 BC041604 AAH41604 BP340339 BX339337 DQ894194 ABM85120 NM_001038707 NP_001033796 NM_020239 NP_064624 |
Function | Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages. {ECO:0000269|PubMed:10816584, ECO:0000269|PubMed:15840583, ECO:0000269|PubMed:17045588}. |
Subcellular Location | Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Recruited to the activated TCR prior actin polymerization. |
Tissue Specificity | Widely expressed. Expressed at higher level in T-lymphocytes, dendritic and whole blood cells. {ECO:0000269|PubMed:15840583}. |
CDC42SE1 fusion protein - Ag3098 from Proteintech Group
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Recombinant Human CDC42 small effector protein 1(CDC42SE1) - CSB-YP868304HU CSB-EP868304HU CSB-BP868304HU CSB-MP868304HU from Cusabio
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CDC42SE1 (transcript variant 2) - TP319709 from Acris Antibodies
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CDC42 small effector protein 1 (CDC42SE1), Recombinant Protein - MBS1464421 from MyBioSource
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CDC42SE1 Recombinant Protein Antigen - NBP1-80780PEP from Novus Biologicals
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CDC42SE1 Peptide, Human - M34GP02814H from Creative Peptides
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