ASRGL1

Gene Symbol	ASRGL1
Entrez Gene	80150
Alt Symbol	ALP, ALP1, CRASH
Species	Human
Gene Type	protein-coding
Description	asparaginase like 1
Other Description	L-asparaginase|L-asparagine amidohydrolase|asparaginase-like 1 protein|asparaginase-like protein 1|beta-aspartyl-peptidase|isoaspartyl dipeptidase|isoaspartyl peptidase/L-asparaginase
Swissprots	Q8NI34 Q9H6F7 B2R7Q0 Q6P1P0 Q567Q4 Q7L266
Accessions	EAW74012 EAW74013 EAW74014 EAW74015 EAW74016 EAW74017 Q7L266 AF411076 AAM28434 AK090908 BAG52245 AK091894 BAG52437 AK225802 AK297158 BAG59656 AK309845 AK313069 BAG35897 BC006267 AAH06267 BC021295 AAH21295 BC064963 AAH64963 BC093070 AAH93070 BP308677 BX640832 DA159051 DT220454 EU831759 ACE87277 EU831837 ACE86596 XM_005274304 XP_005274361 XM_005274305 XP_005274362 XM_005274306 XP_005274363 XM_011545264 XP_011543566 XM_011545265 XP_011543567 XM_011545266 XP_011543568 NM_001083926 NP_001077395 NM_025080 NP_079356
Function	Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. {ECO:0000269|PubMed:19839645}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:11984834}. Note=Midpiece of sperm tail.
Tissue Specificity	Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over-expressed in uterine, mammary, prostatic and ovarian carcinoma. {ECO:0000269|PubMed:11984834, ECO:0000269|PubMed:14654938}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ASRGL1-Over-expression-Lysate - LY15750a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

ASRGL1 293T Cell Transient Overexpression Lysate(Denatured) - H00080150-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ASRGL1 Overexpression Lysate (Denatured) - H00080150-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

ASRGL1 Overexpression Lysate (Native) - NBP2-08432 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ASRGL1 Overexpression Lysate (Native) - NBP2-06243 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ASRGL1 (h4): 293T Lysate - sc-372961 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

Panoply™ Human ASRGL1 Knockdown Stable Cell Line - CSC-DC001062 from Creative biogene Category Cell Line Species Human

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