ASRGL1

Gene Symbol ASRGL1
Entrez Gene 80150
Alt Symbol ALP, ALP1, CRASH
Species Human
Gene Type protein-coding
Description asparaginase like 1
Other Description L-asparaginase|L-asparagine amidohydrolase|asparaginase-like 1 protein|asparaginase-like protein 1|beta-aspartyl-peptidase|isoaspartyl dipeptidase|isoaspartyl peptidase/L-asparaginase
Swissprots Q8NI34 Q9H6F7 B2R7Q0 Q6P1P0 Q567Q4 Q7L266
Accessions EAW74012 EAW74013 EAW74014 EAW74015 EAW74016 EAW74017 Q7L266 AF411076 AAM28434 AK090908 BAG52245 AK091894 BAG52437 AK225802 AK297158 BAG59656 AK309845 AK313069 BAG35897 BC006267 AAH06267 BC021295 AAH21295 BC064963 AAH64963 BC093070 AAH93070 BP308677 BX640832 DA159051 DT220454 EU831759 ACE87277 EU831837 ACE86596 XM_005274304 XP_005274361 XM_005274305 XP_005274362 XM_005274306 XP_005274363 XM_011545264 XP_011543566 XM_011545265 XP_011543567 XM_011545266 XP_011543568 NM_001083926 NP_001077395 NM_025080 NP_079356
Function Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L- Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. {ECO:0000269|PubMed:19839645}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11984834}. Note=Midpiece of sperm tail.
Tissue Specificity Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over-expressed in uterine, mammary, prostatic and ovarian carcinoma. {ECO:0000269|PubMed:11984834, ECO:0000269|PubMed:14654938}.

ASRGL1 (C-17) - sc-249971 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ASRGL1 (N-17) - sc-249969 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ASRGL1 (N-17): sc-249969. Western blot analysis of ASRGL1 expression in non-transfected 293T: sc-117752 (A), human ASRGL1 transfected 293T: sc-372961 (B), HeLa (C), Jurkat (D), K-562 (E) and U-87 MG (F) whole cell lysates.

ASRGL1 (LA-52) - sc-130472 from Santa Cruz Biotechnology

Prices $295.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
ASRGL1 (LA-52): sc-130472. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human salivary gland tissue showing cytoplasmic localization.

Anti-ASRGL1 antibody - ab150832 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U-2 OS cells labeling ASRGL1 with ab150832 at 4 µg/ml.

Anti-ASRGL1 antibody - ab166949 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-ASRGL1 antibody (ab166949) at 1/500 dilution + Human fetal testis lysate

Anti-ASRGL1 antibody - ab168992 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ASRGL1 antibody (ab168992) at 1 µg/mlLane 1 : ASRGL1 transfected 293T lysate Lane 2 : Non-transfected 293T lysate Lysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-ASRGL1 Antibody (clone 5C8) - LS-C133819 from LifeSpan Bioscience

Prices $355.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 5C8
Immunoperoxidase of monoclonal antibody to ASRGL1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml]

Anti-ASRGL1 Antibody (Internal) - LS-C126898 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal

Anti-ASRGL1 Antibody - LS-C306413 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ASRGL1 Antibody - LS-C309537 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ASRGL1 Antibody - LS-C309539 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ASRGL1 Antibody (aa251-300) - LS-C135306 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ASRGL1 antibody LS-C135306 Western blot of Mouse Brain lysate.

Anti-ASRGL1 Antibody (aa2-180) - LS-C179179 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ASRGL1 Antibody (Internal) - LS-C61707 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (1.5 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ASRGL1 Antibody - NBP2-38759 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ASRGL1 Antibody [NBP2-38759] - Lane 1: Marker  [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.  Lane 2: Negative Control.  Lane 3: Overexpression lysate

ASRGL1 Antibody - NBP1-89133 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: ASRGL1 Antibody [NBP1-89133] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & microtubules.

L-Asparaginase Antibody - NBP1-78086 from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: L-Asparaginase Antibody [NBP1-78086] - Lane 1: L-Asparaginase. Lane 2: none. Load: 100 ug per lane. Primary antibody: L-Asparaginase antibody at 1:1000 for overnight at 4C. Secondary antibody: DyLight (TM) 649 rabbit secondary antibody at 1:20,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 32 kDa for L-Asparaginase. Other band(s): L-Asparaginase splice variants and isoforms.

ASRGL1 Antibody - NBP1-00155 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: ASRGL1 Antibody [NBP1-00155] - NBP1-00155 0.5ug/ml staining of Human Tonsil lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ASRGL1 Antibody - H00080150-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: ASRGL1 Antibody [H00080150-B01P] - Analysis of ASRGL1 expression in transfected 293T cell line by ASRGL1 polyclonal antibody.  Lane 1: ASRGL1 transfected lysate(33.88 KDa). Lane 2: Non-transfected lysate.

ASRGL1 Antibody - H00080150-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: ASRGL1 Antibody [H00080150-D01P] - Analysis of ASRGL1 expression in transfected 293T cell line by ASRGL1 polyclonal antibody.Lane 1: ASRGL1 transfected lysate(32.10 KDa).Lane 2: Non-transfected lysate.

ASRGL1 Antibody - H00080150-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: ASRGL1 Antibody [H00080150-B01] - analysis of ASRGL1 expression in transfected 293T cell line by ASRGL1 MaxPab polyclonal antibody (B01). Lane 1: ASRGL1 transfected lysate (32.10 KDa). Lane 2: Non-transfected lysate.

ASRGL1 Antibody - H00080150-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

ASRGL1 Antibody - H00080150-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ASRGL1 Antibody (5C8) - H00080150-M03A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 5C8

Monoclonal Anti-ASRGL1 antibody produced in mouse - SAB1405282 from Sigma-Aldrich

Prices $347.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 5C8
<B>Immunoblotting</B><BR/>Monoclonal Anti-ASRGL1: <B>Cat. No. SAB1405282</B>: Antibody concentration: 1 μg/mL. Specific band of ~45.9 kDa using immunogen protein lysate.
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