HP

Gene Symbol	HP
Entrez Gene	3240
Alt Symbol	BP, HP2ALPHA2, HPA1S
Species	Human
Gene Type	protein-coding
Description	haptoglobin
Other Description	binding peptide|haptoglobin alpha(1S)-beta|haptoglobin alpha(2FS)-beta|haptoglobin, alpha polypeptide|haptoglobin, beta polypeptide|zonulin
Swissprots	Q2PP15 Q6LBY9 Q9UC67 P00737 Q0VAC4 P00738 Q0VAC5 B0AZL5 Q3B7J0
Accessions	AAA88078 AAA88080 AAC27432 ABC40729 CAA25248 CAA25926 EAW59194 EAW59195 EAW59196 EAW59197 P00738 AK055872 BAG51589 AK314700 BAF98793 BC017862 AAH17862 BC058031 AAH58031 BC070299 AAH70299 BC107587 AAI07588 BC121124 AAI21125 BC121125 AAI21126 CB117006 CB134891 K00422 AAA52687 K01763 AAA52684 L29394 AAA52685 M13192 T71743 X00637 CAA25267 XM_005255922 XP_005255979 NM_001126102 NP_001119574 NM_005143 NP_005134
Function	As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. {ECO:0000269|PubMed:21248165}.
Subcellular Location	Secreted.
Tissue Specificity	Expressed by the liver and secreted in plasma.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Dog Haptoglobin full length protein - ab167769 from Abcam Category Protein Prices $609.00 Sizes 100 µg Source Native Species Dog

Human Haptoglobin full length protein - ab168712 from Abcam Category Protein Source Native Species Human

Human Haptoglobin full length protein - ab77872 from Abcam Category Protein Source Native Species Human

Human Haptoglobin full length protein - ab90924 from Abcam Category Protein Source Native Species Human

Human Haptoglobin full length protein - ab196135 from Abcam Category Protein Source HEK 293 cells Species Human

Human Haptoglobin protein fragment - ab177623 from Abcam Category Protein Source E. coli Species Human

Human Haptoglobin protein fragment - ab73587 from Abcam Category Protein Source E. coli Species Human

Human Haptoglobulin beta full length protein - ab83165 from Abcam Category Protein Source E. coli Species Human

Human Haptoglobulin beta full length protein - ab83167 from Abcam Category Protein Source E. coli Species Human

Human Haptoglobulin beta full length protein - ab63120 from Abcam Category Protein Source E. coli Species Human

Pig Haptoglobin full length protein - ab168904 from Abcam Category Protein Source Native Species Pig

Rat Haptoglobin full length protein - ab167775 from Abcam Category Protein Source Native Species Rat

HP / Haptoglobin Antibody Blocking Peptide - LS-E402 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HP / Haptoglobin Antibody Blocking Peptide - LS-E27790 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HP / Haptoglobin Antibody Blocking Peptide - LS-E27791 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Haptoglobin Recombinant Protein - H00003240-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

HP-Antibody-Center-Blocking-peptide - BP10680c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HP-Antibody-Center-Blocking-Peptide - BP8929c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant rat Haptoglobin protein (OPCA01129) - OPCA01129 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Rat

Human Plasma Haptoglobin Protein (OPMA04250) - OPMA04250 from Aviva Systems Biology Category Protein Prices $285.00 Sizes 5 mg Species Human

Haptoglobin Human - Human Haptoglobin Protein (OPPA01435) - OPPA01435 from Aviva Systems Biology Category Protein Prices $180.00 Sizes 200 µg Source Pooled human plasma Species Human

Haptoglobin Protein (OPPA01442) - OPPA01442 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

NATIVE Human HAPTOGLOBIN Protein (OPSA11757) - OPSA11757 from Aviva Systems Biology Category Protein Prices $300.00 Sizes 1 mg Species Human

Human Haptoglobin protein - orb81151 from Biorbyt Category Protein Prices $366.00, $578.00 Sizes 200 μg, 1 mg Source Pooled human plasma Species Human

Human Haptoglobin protein - orb81150 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E.coli

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