HP

Gene Symbol HP
Entrez Gene 3240
Alt Symbol BP, HP2ALPHA2, HPA1S
Species Human
Gene Type protein-coding
Description haptoglobin
Other Description binding peptide|haptoglobin alpha(1S)-beta|haptoglobin alpha(2FS)-beta|haptoglobin, alpha polypeptide|haptoglobin, beta polypeptide|zonulin
Swissprots Q2PP15 Q6LBY9 Q9UC67 P00737 Q0VAC4 P00738 Q0VAC5 B0AZL5 Q3B7J0
Accessions AAA88078 AAA88080 AAC27432 ABC40729 CAA25248 CAA25926 EAW59194 EAW59195 EAW59196 EAW59197 P00738 AK055872 BAG51589 AK314700 BAF98793 BC017862 AAH17862 BC058031 AAH58031 BC070299 AAH70299 BC107587 AAI07588 BC121124 AAI21125 BC121125 AAI21126 CB117006 CB134891 K00422 AAA52687 K01763 AAA52684 L29394 AAA52685 M13192 T71743 X00637 CAA25267 XM_005255922 XP_005255979 NM_001126102 NP_001119574 NM_005143 NP_005134
Function As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. {ECO:0000269|PubMed:21248165}.
Subcellular Location Secreted.
Tissue Specificity Expressed by the liver and secreted in plasma.

Haptoglobin CRISPR/Cas9 KO Plasmid (h) - sc-401468 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin HDR Plasmid (h) - sc-401468-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin Double Nickase Plasmid (h) - sc-401468-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin Double Nickase Plasmid (h2) - sc-401468-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin CRISPR Activation Plasmid (h) - sc-401468-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin CRISPR Activation Plasmid (h2) - sc-401468-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin Lentiviral Activation Particles (h) - sc-401468-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin Lentiviral Activation Particles (h2) - sc-401468-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Haptoglobin siRNA (h) - sc-72093 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Haptoglobin shRNA Plasmid (h) - sc-72093-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Haptoglobin shRNA (h) Lentiviral Particles - sc-72093-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10268 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00728 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00728

HP siRNA (Human) - CRH2224 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HP - MBS8237478 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HP (NM_005143.3) - SHH314509 from Creative biogene

Category siRNA
Species Reactivities Human

Human HP siRNA - orb262726 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HP shRNA Plasmid (Human) - CHH2224 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HP miRNA 3'UTR clone - MiUTR3H-00992 from Creative biogene

Species Reactivities Human

HP miRNA 3'UTR clone - MiUTR3H-00993 from Creative biogene

Species Reactivities Human
Search more