Gene Symbol | RGS7BP |
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Entrez Gene | 401190 |
Alt Symbol | R7BP |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 7 binding protein |
Other Description | R7 family-binding protein|regulator of G-protein signaling 7-binding protein |
Swissprots | B7Z3X1 Q6MZT1 |
Accessions | EAW51372 Q6MZT1 AK294808 BAG57927 AK296443 BAH12357 AK296494 BAG59129 BC140707 AAI40708 BX640900 CAE45947 DA211241 DA404068 DA417118 DC342795 XM_005248502 XP_005248559 XR_948251 NM_001029875 NP_001025046 NM_001271890 NP_001258819 NM_001271891 NP_001258820 NR_073511 |
Function | Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Note=Shuttling between the plasma membrane, the cytoplasm and the nucleus is regulated by palmitoylation. {ECO:0000250}. |
R7BP (D-15) - sc-50170 from Santa Cruz Biotechnology
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R7BP (W-16) - sc-50173 from Santa Cruz Biotechnology
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R7BP (FL-246) - sc-99235 from Santa Cruz Biotechnology
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Anti-RGS7BP antibody - ab150857 from Abcam
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RGS7BP Antibody - NBP2-14504 from Novus Biologicals
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Anti-RGS7BP antibody produced in rabbit - HPA039600 from Sigma-Aldrich
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RGS7BP Antibody - middle region (ARP69891_P050) - ARP69891_P050 from Aviva Systems Biology
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Anti-RGS7BP (aa 86-178) polyclonal antibody - DPABH-03003 from Creative Diagnostics
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RGS7BP antibody - TA334912 from Acris Antibodies
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Anti-RGS7BP Antibody A15167 - A15167 from Boster Bio
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RGS7BP Antibody - middle region : Biotin (ARP69891_P050-Biotin) - ARP69891_P050-Biotin from Aviva Systems Biology
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RGS7BP Antibody - middle region : FITC (ARP69891_P050-FITC) - ARP69891_P050-FITC from Aviva Systems Biology
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RGS7BP Antibody - middle region : HRP (ARP69891_P050-HRP) - ARP69891_P050-HRP from Aviva Systems Biology
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