EYA4

Gene Symbol	EYA4
Entrez Gene	2070
Alt Symbol	CMD1J, DFNA10
Species	Human
Gene Type	protein-coding
Description	EYA transcriptional coactivator and phosphatase 4
Other Description	dJ78N10.1 (eyes absent)|eyes absent homolog 4
Swissprots	B7Z7F7 O95677 O95464 O95679 Q8IW39 Q9NTR7
Accessions	CAA76891 EAW48004 EAW48005 EAW48006 O95677 AJ007993 CAA07816 AJ007994 CAA07817 AK295798 BAG58618 AK299378 BAG61368 AK301950 BAH13593 AW613879 BC014193 AAH14193 BC030588 BC041063 AAH41063 BX490250 DA760903 EU446856 ABZ92385 Y17114 CAA76636 XM_005266851 XP_005266908 XM_005266852 XP_005266909 XM_005266853 XP_005266910 XM_011535540 XP_011533842 XM_011535541 XP_011533843 XM_011535542 XP_011533844 NM_001301012 NP_001287941 NM_001301013 NP_001287942 NM_004100 NP_004091 NM_172103 NP_742101 NM_172105 NP_742103 NM_172104
Function	Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Tissue Specificity	Highly expressed in heart and skeletal muscle. {ECO:0000269|PubMed:15735644}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human EYA4 full length protein - ab132521 from Abcam Category Protein Source Wheat germ Species Human

Human EYA4 peptide - ab48040 from Abcam Category Peptide Species Human

EYA4 Antibody Blocking Peptide - LS-E25983 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EYA4 Antibody Blocking Peptide - LS-E10073 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

EYA4 Recombinant Protein - H00002070-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

EYA4-Antibody-C-term-Blocking-Peptide - BP9330b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

EYA4 blocking peptide - GTX89345-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

EYA4 Peptide - AC21-0811-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

EYA4 - H00002070-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

EYA4 - H00002070-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

EYA4 Peptide - 45-559P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

EYA4 fusion protein - ag20466 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

EYA4 fusion protein - Ag20457 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Eyes absent homolog 4(EYA4) - CSB-YP007909HU CSB-EP007909HU CSB-BP007909HU CSB-MP007909HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

EYA4, Peptide - MBS425005 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse

EYA4 Recombinant Protein Antigen - NBP1-85548PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

EYA4 Recombinant Protein Antigen - NBP1-85547PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

EYA4 Protein - NBP1-85546PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

EYA4 Peptide, Human - M34GP05159H from Creative Peptides Category Peptide Source Synthetic. Species Human

Eyes absent homolog 4 (EYA4), Recombinant Protein - MBS1223010 from MyBioSource Category Protein Prices $1,435.00, $1,435.00, $1,665.00, $1,665.00, $2,435.00, $2,435.00, $2,880.00, $2,880.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

EYA4 Immunizing peptide - orb15168 from Biorbyt Category Peptide

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