| Gene Symbol | CXCR1 |
|---|---|
| Entrez Gene | 3577 |
| Alt Symbol | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
| Species | Human |
| Gene Type | protein-coding |
| Description | chemokine (C-X-C motif) receptor 1 |
| Other Description | C-X-C chemokine receptor type 1|CXC-R1|CXCR-1|IL-8 receptor type 1|IL-8R A|high affinity interleukin-8 receptor A|interleukin 8 receptor, alpha|interleukin-8 receptor type 1|interleukin-8 receptor type A |
| Swissprots | Q2YEF8 B2R6Q3 P25024 Q2YEG7 Q8N6T6 Q9P2T9 Q9P2U2 Q2YEG4 Q9P2T8 Q2YEG8 Q9P2U1 Q2YEG5 Q6IN95 Q53R18 Q9P2U0 |
| Accessions | AAA59160 AAA64378 AAT46689 AAX93212 AAY21512 AAY21513 AAY21514 AAY21515 AAY21516 AAY21519 AAY21522 AAY21523 BAA92290 BAA92291 BAA92292 BAA92293 BAA92294 CAA46688 EAW70590 P25024 AK298647 BAG60821 AK309632 AK312668 BAG35550 BC028221 AAH28221 BC072397 AAH72397 CA425329 CR541994 CAG46791 CR542029 CAG46826 DQ891718 ABM82644 DQ894895 ABM85821 L19591 AAB59436 M68932 AAA59159 U11871 AAA64379 NM_000634 NP_000625 |
| Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Top Pathways | Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, Endocytosis, Chemokine signaling pathway |
Human CXCR1 ELISA Kit (Sandwich ELISA) - LS-F3976 from LifeSpan Bioscience
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Mouse CXCR1 ELISA Kit (Sandwich ELISA) - LS-F6187 from LifeSpan Bioscience
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Rabbit CXCR1 ELISA Kit (Sandwich ELISA) - LS-F6249 from LifeSpan Bioscience
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Rat CXCR1 ELISA Kit (Sandwich ELISA) - LS-F6250 from LifeSpan Bioscience
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Human CXCR1 ELISA Kit (Sandwich ELISA) - LS-F11255 from LifeSpan Bioscience
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Rat CXCR1 ELISA Kit (Sandwich ELISA) - LS-F11256 from LifeSpan Bioscience
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Human IL8Ra ELISA Kit - abx151952 from Abbexa
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C-X-C chemokine receptor type 1, CXCR1, Human, ELISA Kit - E0019h from ARP American Research Products
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CXC-Chemokine Receptor 1, CXCR1, Human, ELISA Kit - E-EL-H0853 from ARP American Research Products
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CXC-Chemokine Receptor 1, CXCR1, Rabbit, ELISA Kit - E-EL-RB0208 from ARP American Research Products
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CXC-Chemokine Receptor 1, CXCR1, Chicken, ELISA Kit - E-EL-Ch0197 from ARP American Research Products
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CXC-Chemokine Receptor 1, CXCR1, Porcine, ELISA Kit - E-EL-P2253 from ARP American Research Products
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CXC-Chemokine Receptor 1, CXCR1, Sheep, ELISA Kit - E-EL-S0624 from ARP American Research Products
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CXC-Chemokine Receptor 1, CXCR1, Monkey, ELISA Kit - E-EL-MK2012 from ARP American Research Products
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Human Sil-8R/cd128 ELISA Kit - HS0269 from NeoScientific
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Human CXCR1 ELISA Kit - HC0859 from NeoScientific
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Rat Sil-8R/cd128 ELISA Kit - RS0269 from NeoScientific
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Guinea Pig Sil-8R/cd128 ELISA Kit - GS0269 from NeoScientific
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Bovine Sil-8R/cd128 ELISA Kit - BS0269 from NeoScientific
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Canine Sil-8R/cd128 ELISA Kit - CS0269 from NeoScientific
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Porcine Sil-8R/cd128 ELISA Kit - PS0269 from NeoScientific
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Goat Sil-8R/cd128 ELISA Kit - GTS0269 from NeoScientific
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Rabbit Sil-8R/cd128 ELISA Kit - RTS0269 from NeoScientific
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Anserine CXCR1 ELISA Kit - AC0859 from NeoScientific
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Anserine Sil-8R/cd128 ELISA Kit - AS0269 from NeoScientific
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