Gene Symbol | CXCR1 |
---|---|
Entrez Gene | 3577 |
Alt Symbol | C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) receptor 1 |
Other Description | C-X-C chemokine receptor type 1|CXC-R1|CXCR-1|IL-8 receptor type 1|IL-8R A|high affinity interleukin-8 receptor A|interleukin 8 receptor, alpha|interleukin-8 receptor type 1|interleukin-8 receptor type A |
Swissprots | Q2YEF8 B2R6Q3 P25024 Q2YEG7 Q8N6T6 Q9P2T9 Q9P2U2 Q2YEG4 Q9P2T8 Q2YEG8 Q9P2U1 Q2YEG5 Q6IN95 Q53R18 Q9P2U0 |
Accessions | AAA59160 AAA64378 AAT46689 AAX93212 AAY21512 AAY21513 AAY21514 AAY21515 AAY21516 AAY21519 AAY21522 AAY21523 BAA92290 BAA92291 BAA92292 BAA92293 BAA92294 CAA46688 EAW70590 P25024 AK298647 BAG60821 AK309632 AK312668 BAG35550 BC028221 AAH28221 BC072397 AAH72397 CA425329 CR541994 CAG46791 CR542029 CAG46826 DQ891718 ABM82644 DQ894895 ABM85821 L19591 AAB59436 M68932 AAA59159 U11871 AAA64379 NM_000634 NP_000625 |
Function | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, Endocytosis, Chemokine signaling pathway |
Human CXCR1 full length protein - ab158759 from Abcam
|
||||||||||
CXCR1 Antibody Blocking Peptide - LS-E27389 from LifeSpan Bioscience
|
||||||||||
CXCR1 Antibody Blocking Peptide - LS-E29324 from LifeSpan Bioscience
|
||||||||||
CXCR1 Antibody Blocking Peptide - LS-E29329 from LifeSpan Bioscience
|
||||||||||
CXCR1 Antibody Blocking Peptide - LS-E29331 from LifeSpan Bioscience
|
||||||||||
CXCR1/IL-8 RA Recombinant Protein - H00003577-P01 from Novus Biologicals
|
||||||||||
CXCR1 blocking peptide - GTX88098-PEP from GeneTex
|
||||||||||
CXCR1 Protein Lysate (APL10972) - APL10972 from Aviva Systems Biology
|
||||||||||
CXCR1 peptide - orb72584 from Biorbyt
|
||||||||||
CD181 Blocking Peptide - abx064166 from Abbexa
|
||||||||||
CXCR1 Peptide - AC21-2213-P from Abcore
|
||||||||||
CD181 / IL8RA - H00003577-G01 from Acris Antibodies
|
||||||||||
CD181 / IL8RA - H00003577-P01 from Acris Antibodies
|
||||||||||
CD181 / IL8RA - H00003577-P01-10 from Acris Antibodies
|
||||||||||
CD181 / IL8RA - H00003577-P01-25 from Acris Antibodies
|
||||||||||
CD181 / IL8RA Control Peptide - AP09952CP-N from Acris Antibodies
|
||||||||||
CD181 / IL8RA Control Peptide - AP09953CP-N from Acris Antibodies
|
||||||||||
IL8RA Peptide - 42-606P from ProSci
|
||||||||||
IL8RA fusion protein - ag4417 from Proteintech Group
|
||||||||||
Recombinant Human CXCR1 - CXCR1-235H from Creative Biomart
|
||||||||||
Recombinant Interleukin 8 Receptor Alpha (IL8Ra) - RPA019Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Interleukin 8 Receptor Alpha (IL8Ra) - RPA019Mu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Interleukin 8 Receptor Alpha (IL8Ra) - RPA019Mu02 from Uscn Life Science Inc.
|
||||||||||
Recombinant Interleukin 8 Receptor Alpha (IL8Ra) - RPA019Ra01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Interleukin 8 Receptor Alpha (IL8Ra) - RPA019Rb01 from Uscn Life Science Inc.
|