CXCR1

Gene Symbol	CXCR1
Entrez Gene	3577
Alt Symbol	C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Species	Human
Gene Type	protein-coding
Description	chemokine (C-X-C motif) receptor 1
Other Description	C-X-C chemokine receptor type 1|CXC-R1|CXCR-1|IL-8 receptor type 1|IL-8R A|high affinity interleukin-8 receptor A|interleukin 8 receptor, alpha|interleukin-8 receptor type 1|interleukin-8 receptor type A
Swissprots	Q2YEF8 B2R6Q3 P25024 Q2YEG7 Q8N6T6 Q9P2T9 Q9P2U2 Q2YEG4 Q9P2T8 Q2YEG8 Q9P2U1 Q2YEG5 Q6IN95 Q53R18 Q9P2U0
Accessions	AAA59160 AAA64378 AAT46689 AAX93212 AAY21512 AAY21513 AAY21514 AAY21515 AAY21516 AAY21519 AAY21522 AAY21523 BAA92290 BAA92291 BAA92292 BAA92293 BAA92294 CAA46688 EAW70590 P25024 AK298647 BAG60821 AK309632 AK312668 BAG35550 BC028221 AAH28221 BC072397 AAH72397 CA425329 CR541994 CAG46791 CR542029 CAG46826 DQ891718 ABM82644 DQ894895 ABM85821 L19591 AAB59436 M68932 AAA59159 U11871 AAA64379 NM_000634 NP_000625
Function	Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction, Epithelial cell signaling in Helicobacter pylori infection, Endocytosis, Chemokine signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CXCR1 overexpression lysate - LY400214 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CXCR1 293 Cell Lysate - 400278 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CXCR1/IL-8 RA Overexpression Lysate (Native) - NBL1-11968 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

IL-8RA (h3): 293T Lysate - sc-176056 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CXCR1 Over-expression Lysate Product - GWB-125C2E from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CXCR1/IL-8 RA Overexpression Lysate (Native) - NBP2-10476 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human CXCR1 Knockdown Stable Cell Line - CSC-DC003874 from Creative biogene Category Cell Line Species Human

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