Gene Symbol | PHKA1 |
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Entrez Gene | 5255 |
Alt Symbol | PHKA |
Species | Human |
Gene Type | protein-coding |
Description | phosphorylase kinase, alpha 1 (muscle) |
Other Description | phosphorylase b kinase regulatory subunit alpha skeletal muscle isoform|phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform|phosphorylase kinase alpha M subunit|phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis |
Swissprots | Q2M3D7 P46020 B7ZL07 B7ZL05 |
Accessions | EAW71825 EAW71826 P46020 AK123357 AW450116 BC104944 AAI04945 BC143499 AAI43500 BC143501 AAI43502 BJ998054 BX647542 DA171597 DA998603 DR002787 X73874 CAA52083 X73878 XM_006724661 XP_006724724 NM_001122670 NP_001116142 NM_001172436 NP_001165907 NM_002637 NP_002628 |
Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Muscle specific. Isoform 1 is predominant in vastus lateralis muscle. Isoform 2 predominates slightly in heart, and it predominates clearly in the other tissues tested. |
Top Pathways | Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway |
PHKA1 (D-14) - sc-168945 from Santa Cruz Biotechnology
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PHKA1 (E-15) - sc-168946 from Santa Cruz Biotechnology
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Anti-PHKA1 antibody - ab96752 from Abcam
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Anti-PHKA1 antibody - ab70068 from Abcam
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Anti-PHKA1 antibody [EPR12118] - ab176338 from Abcam
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Anti-PHKA1 Antibody (aa828-1062) - LS-C186068 from LifeSpan Bioscience
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PHKA1 Antibody - NBP1-87281 from Novus Biologicals
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PHKA1 Antibody - H00005255-A01 from Novus Biologicals
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PHKA1 Polyclonal Antibody - bs-5008R from Bioss
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Anti-PHKA1 (C-terminal) antibody produced in rabbit - SAB2701040 from Sigma-Aldrich
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Anti-KPB1, N-Terminal antibody produced in rabbit - SAB4502189 from Sigma-Aldrich
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PHKA1 Antibody (OAAF02273) - OAAF02273 from Aviva Systems Biology
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PHKA1 antibody - orb73647 from Biorbyt
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PHKA1 antibody (OAGA00764) - OAGA00764 from Aviva Systems Biology
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PHKA1 antibody - 70R-13276 from Fitzgerald
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PHKA1 / PHKA antibody - 24279-1-AP from Acris Antibodies
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PHKA1 / PHKA antibody - H00005255-A01 from Acris Antibodies
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Rabbit Anti-Human PHKA1, C-term - 107-10839 from RayBiotech
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Anti-PHKA1/2 antibody - STJ95065 from St John's Laboratory Ltd
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PHKA1 antibody - 24279-1-AP from Proteintech Group
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KPB1/2 Polyclonal Antibody - PA002163-C10626 from Syd Labs
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PHKA1 Antibody - 37822 from Signalway Antibody
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KPB1/2 Antibody - 33776 from Signalway Antibody
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PHKA1 antibody - 22521 from Signalway Antibody
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KPB1/2 Antibody - E11-10626C from Enogene
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