Gene Symbol | PHKA1 |
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Entrez Gene | 5255 |
Alt Symbol | PHKA |
Species | Human |
Gene Type | protein-coding |
Description | phosphorylase kinase, alpha 1 (muscle) |
Other Description | phosphorylase b kinase regulatory subunit alpha skeletal muscle isoform|phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform|phosphorylase kinase alpha M subunit|phosphorylase kinase, alpha 1 (muscle), muscle glycogenosis |
Swissprots | Q2M3D7 P46020 B7ZL07 B7ZL05 |
Accessions | EAW71825 EAW71826 P46020 AK123357 AW450116 BC104944 AAI04945 BC143499 AAI43500 BC143501 AAI43502 BJ998054 BX647542 DA171597 DA998603 DR002787 X73874 CAA52083 X73878 XM_006724661 XP_006724724 NM_001122670 NP_001116142 NM_001172436 NP_001165907 NM_002637 NP_002628 |
Function | Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin. |
Subcellular Location | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
Tissue Specificity | Muscle specific. Isoform 1 is predominant in vastus lateralis muscle. Isoform 2 predominates slightly in heart, and it predominates clearly in the other tissues tested. |
Top Pathways | Insulin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway |
Human PHKA1 protein fragment - ab159107 from Abcam
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Recombinant Human PHKA1 Protein - H00005255-Q01 from Novus Biologicals
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PHKA1-Antibody-Center-Blocking-peptide - BP12245c from Abgent, a WuXi AppTec company
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PHKA1 / PHKA - H00005255-Q01-10 from Acris Antibodies
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PHKA1 / PHKA - H00005255-Q01-25 from Acris Antibodies
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PHKA1 fusion protein - ag17998 from Proteintech Group
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PHKA1 fusion protein - Ag19057 from Proteintech Group
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Recombinant Human Phosphorylase b kinase regulatory subunit alpha, skeletal musc - CSB-YP017922HU CSB-EP017922HU CSB-BP017922HU CSB-MP017922HU from Cusabio
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PHKA1 / PHKA (transcript variant 1) - TP311553 from Acris Antibodies
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PHKA1 / PHKA (transcript variant 2) - TP326362 from Acris Antibodies
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Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (PHKA1), partial, Recombinant Protein - MBS952750 from MyBioSource
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PHKA1 Recombinant Protein Antigen - NBP1-87281PEP from Novus Biologicals
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PHKA1 Peptide, Human - M34GP11708H from Creative Peptides
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