CACNA1E

Gene Symbol CACNA1E
Entrez Gene 777
Alt Symbol BII, CACH6, CACNL1A6, Cav2.3
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, R type, alpha 1E subunit
Other Description brain calcium channel II|calcium channel, L type, alpha-1 polypeptide|calcium channel, R type, alpha-1 polypeptide|calcium channel, voltage-dependent, alpha 1E subunit|voltage-dependent R-type calcium channel subunit alpha-1E|voltage-dependent calcium channel alpha 1E subunit|voltage-gated calcium channel alpha 1E subunit|voltage-gated calcium channel alpha subunit Cav2.3|voltage-gated calcium channel subunit alpha Cav2.3
Swissprots Q14580 Q15878 B1AM12 Q14581 B1AM14 B1AM13
Accessions AAD38389 AAF37687 AAF37688 CAB81554 EAW91103 EAW91104 EAW91105 EAW91106 EAW91107 EAW91108 EAW91109 EAW91110 Q15878 AA349993 AB209499 BAD92736 AK096563 AK309070 AW452628 BC037800 BC172376 AAI72376 BE504178 BI914369 BP230397 CD580303 L27745 AAA72125 L29384 AAA59204 L29385 AAA59205 R11722 XM_011509971 XP_011508273 NM_000721 NP_000712 NM_001205293 NP_001192222 NM_001205294 NP_001192223
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega- conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega- Aga-IVA). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in neuronal tissues and in kidney.
Top Pathways Type II diabetes mellitus, MAPK signaling pathway, Calcium signaling pathway

R-type Ca ++ CP α1E (C-20) - sc-16225 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
R-type Ca<sup>++</sup> CP α1E (C-20): sc-16225. Western blot analysis of R-type Ca<sup>++</sup> CP α1E expression in Caki-1 (A) and SK-N-MC (B) whole cell lysates.

R-type Ca ++ CP α1E (H-60) - sc-28618 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
R-type Ca<sup>++</sup> CP α1E (H-60): sc-28618. Immunofluorescence staining of normal mouse skin frozen section showing membrane staining.

Anti-CACNA1E / Cav2.3 Antibody - LS-C26748 from LifeSpan Bioscience

Prices $330.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CACNA1E / Cav2.3 Antibody (C-Terminus) - LS-C94030 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-CACNA1E / Cav2.3 Antibody - LS-C140728 from LifeSpan Bioscience

Prices $460.00
Sizes 10 blot
Host Rabbit
Clonality Polyclonal

Anti-CACNA1E / Cav2.3 Antibody - LS-C341056 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CACNA1E Antibody - NBP1-20106 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACNA1E Antibody - NBP2-14431 from Novus Biologicals

Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CACNA1E Antibody [NBP2-14431] - Staining of human colon shows strong granular cytoplasmic positivity in glandular cells.

CACH6/Cav2.3 Polyclonal Antibody - bs-3933R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA1E antibody produced in rabbit - SAB4300837 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA1E antibody produced in rabbit - HPA042515 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CACNA1E:<B>Cat. No. HPA042515</B>: Immunohistochemical staining of human colon shows strong granular cytoplasmic positivity in glandular cells.

CACH6 antibody (FITC) - orb8625 from Biorbyt

Prices $315.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-3933R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-3933R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-3933R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-3933R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, Cy3 Conjugated - bs-3933R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, Cy5 Conjugated - bs-3933R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, Cy5.5 Conjugated - bs-3933R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, Cy7 Conjugated - bs-3933R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, FITC Conjugated - bs-3933R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-CACH6/Cav2.3 Polyclonal Antibody, PE Conjugated - bs-3933R-PE from Bioss

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, Biotin Conjugated - bs-3933R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACH6/Cav2.3 Polyclonal Antibody, HRP Conjugated - bs-3933R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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