ZC3H8

Gene Symbol	ZC3H8
Entrez Gene	84524
Alt Symbol	Fliz1, ZC3HDC8
Species	Human
Gene Type	protein-coding
Description	zinc finger CCCH-type containing 8
Other Description	zinc finger CCCH domain-containing protein 8|zinc finger CCCH type domain containing 8|zinc finger CCCH-type domain containing 8
Swissprots	Q9BZ75 Q8N5P1
Accessions	AAY14855 AAY24050 EAW52103 Q8N5P1 AF334161 AAK13496 AK315329 BC032001 AAH32001 BG773518 CV574571 HQ448678 ADQ33156 XM_005263826 XP_005263883 XM_011511998 XP_011510300 NM_032494 NP_115883
Function	Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. {ECO:0000250, ECO:0000269|PubMed:12077251, ECO:0000269|PubMed:12153508, ECO:0000269|PubMed:23932780}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:23932780}. Note=Colocalizes with coilin in subnuclear cajal and histone locus bodies. Translocates in the LEC complex to cajal and histone locus bodies at snRNA genes in a ICE1-dependent manner. Associates to transcriptionally active chromatin at snRNA genes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ZC3H8 Antibody Blocking Peptide - LS-E1008 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZC3H8-Antibody-N-term-Blocking-peptide - BP11463a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZC3H8 Blocking Peptide - abx064010 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

ZC3H8 fusion protein - Ag23514 from Proteintech Group Category Protein Prices $199.00 Sizes 50 Source E. coli -derived, PGEX-4T Species Human

ZC3H8 Blocking Peptide - CBP2816 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

ZC3H8 Peptide - BS5770P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Zinc finger CCCH domain-containing protein 8(ZC3H8) - CSB-YP854047HU CSB-EP854047HU CSB-BP854047HU CSB-MP854047HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ZC3H8 (full length, N-term HIS tag) - TP760094 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

Zinc finger CCCH domain-containing protein 8 (ZC3H8) , Recombinant Protein - MBS1421735 from MyBioSource Category Protein Prices $1,625.00, $1,625.00, $2,090.00, $2,090.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ZC3H8 Recombinant Protein Antigen - NBP2-33980PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZC3H8 Recombinant Protein Antigen - NBP1-84661PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZC3H8 Peptide, Human - M34GP17723H from Creative Peptides Category Peptide Source Synthetic. Species Human

ZC3H8 peptide - orb218679 from Biorbyt Category Peptide Species Human, Mouse

Recombinant Human ZC3H8 Protein, His-tagged - ZC3H8-104H from Creative Biomart Category Protein Source E. coli Species Human

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