CPLX2

Gene Symbol	CPLX2
Entrez Gene	10814
Alt Symbol	921-L, CPX-2, CPX2, Hfb1
Species	Human
Gene Type	protein-coding
Description	complexin 2
Other Description	CPX II|complexin II|complexin-2|synaphin 1|synaphin-1
Swissprots	Q52M15 B2RAG2 Q6PUV4
Accessions	EAW61366 EAW61367 Q6PUV4 AK055043 AK094266 AK124837 AK126590 AK293819 BAG57224 AK314177 BAG36859 AL512758 AL707430 AY576870 AAS93622 BC039560 BC052974 BC065485 BC093706 AAH93706 BC112287 AAI12288 BI197868 BN000499 CAG26663 BN000500 CAG26664 U35100 AAC50229 Y15167 XM_005265798 XP_005265855 XM_005265799 XP_005265856 XM_011534419 XP_011532721 NM_001008220 NP_001008221 NM_006650 NP_006641
Function	Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm, cytosol. Note=Enriched at synaptic-releasing sites in mature neurons. {ECO:0000250}.
Tissue Specificity	Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia. {ECO:0000269|PubMed:11483314, ECO:0000269|PubMed:11576753, ECO:0000269|PubMed:15906159, ECO:0000269|PubMed:16162394, ECO:0000269|PubMed:9853440}.
Top Pathways	Synaptic vesicle cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CPLX2 / Complexin 2 ELISA Kit (Competitive EIA) - LS-F7514 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 246.91 pg/ml Range 246.91-20000 pg/ml

Human Complexin 2 ELISA Kit - abx151144 from Abbexa Category ELISA Kit Sensitivity 84.2 pg/ml Range 246.91 pg/ml - 20000 pg/ml

Complexin 2 (CPLX2), Human, ELISA Kit - CEF332Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 84.2pg/mL Range 246.9-20,000pg/mL

Complexin-2 (CPLX2), Human, ELISA Kit - E01C2003 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

Complexin 2, ELISA Kit - MBS072477 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2, ELISA Kit - MBS096546 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2, ELISA Kit - MBS096299 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2, ELISA Kit - MBS104778 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2, ELISA Kit - MBS083558 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2, ELISA Kit - MBS081613 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2, ELISA Kit - MBS099581 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2 (CPLX2), ELISA Kit - MBS7244588 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin 2 (CPLX2), ELISA Kit - MBS2020555 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 84.2pg/mL. Range 246.91-20000pg/mL

Complexin-2 (CPLX2), ELISA Kit - MBS7213824 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7201540 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7205151 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7247148 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7208042 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7217791 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7236514 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7214791 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7233768 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Complexin-2 (CPLX2), ELISA Kit - MBS7203822 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

ELISA Kit for Complexin 2 (CPLX2) - CEF332Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 84.2pg/mL. Range 246.91-20000pg/mL The standard curve concentrations used for the ELISA's were 20000pg/mL, 6666.67pg/mL, 2222.22pg/mL, 740.74pg/mL, 246.91pg/mL

Human Complexin 2 (CPLX2) ELISA Kit - EKU03434 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 84.2 pg/mL Range 246.91-20000 pg/mL

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