CPLX2

Gene Symbol CPLX2
Entrez Gene 10814
Alt Symbol 921-L, CPX-2, CPX2, Hfb1
Species Human
Gene Type protein-coding
Description complexin 2
Other Description CPX II|complexin II|complexin-2|synaphin 1|synaphin-1
Swissprots Q52M15 B2RAG2 Q6PUV4
Accessions EAW61366 EAW61367 Q6PUV4 AK055043 AK094266 AK124837 AK126590 AK293819 BAG57224 AK314177 BAG36859 AL512758 AL707430 AY576870 AAS93622 BC039560 BC052974 BC065485 BC093706 AAH93706 BC112287 AAI12288 BI197868 BN000499 CAG26663 BN000500 CAG26664 U35100 AAC50229 Y15167 XM_005265798 XP_005265855 XM_005265799 XP_005265856 XM_011534419 XP_011532721 NM_001008220 NP_001008221 NM_006650 NP_006641
Function Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm, cytosol. Note=Enriched at synaptic-releasing sites in mature neurons. {ECO:0000250}.
Tissue Specificity Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia. {ECO:0000269|PubMed:11483314, ECO:0000269|PubMed:11576753, ECO:0000269|PubMed:15906159, ECO:0000269|PubMed:16162394, ECO:0000269|PubMed:9853440}.
Top Pathways Synaptic vesicle cycle

Human-CPLX2-cDNA-Clone - DC09713 from Abgent, a WuXi AppTec company

Prices $180.90
Sizes 10 µg
Species Human
Accession BC112287

CPLX2 - MBS1268954 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC112287

Human CPLX2 cDNA clone(NM_001008220.1) - CDFH004163 from Creative Biomart

Species Human
Accession NM_001008220.1

Human CPLX2 cDNA clone(NM_006650.3) - CDFH004164 from Creative Biomart

Species Human
Accession NM_006650.3

Human CPLX2 ORF Clone(NM_006650.3) - CDCL159607 from Creative Biomart

Species Human
Accession NM_006650.3

Human CPLX2 ORF Clone(NM_006650.3) - CDCR293221 from Creative Biomart

Species Human
Accession NM_006650.3

Human CPLX2 ORF Clone(NM_006650.3) - CDCR293222 from Creative Biomart

Species Human
Accession NM_006650.3

Human CPLX2 ORF Clone(NM_006650.3) - CDCR293223 from Creative Biomart

Species Human
Accession NM_006650.3

Human CPLX2 ORF Clone(NM_001008220.1) - CDCR340351 from Creative Biomart

Species Human
Accession NM_001008220.1

Human CPLX2 ORF Clone(NM_001008220.1) - CDCR340352 from Creative Biomart

Species Human
Accession NM_001008220.1

Human CPLX2 ORF Clone(NM_001008220.1) - CDCR340353 from Creative Biomart

Species Human
Accession NM_001008220.1

Human CPLX2 ORF Clone(NM_006650.3) - CDCR293221 from Creative biogene

Species Human

Human CPLX2 ORF Clone(NM_001008220.1) - CDCR340351 from Creative biogene

Species Human

Human CPLX2 ORF Clone (BC112287) - CDCS406347 from Creative biogene

Species Human
Accession Q6PUV4

Human CPLX2 cDNA Clone(NM_001008220.1) - CDFH004163 from Creative biogene

Species Human

Human CPLX2 cDNA Clone(NM_006650.3) - CDFH004164 from Creative biogene

Species Human
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