HOOK2

Gene Symbol HOOK2
Entrez Gene 29911
Alt Symbol HK2
Species Human
Gene Type protein-coding
Description hook microtubule-tethering protein 2
Other Description h-hook2|hHK2|hook homolog 2|protein Hook homolog 2
Swissprots Q96ED9 O60562
Accessions EAW84305 EAW84306 Q96ED9 AF044924 AAC09299 AK129729 BAC85229 BC012443 AAH12443 DB474423 DQ891339 ABM82265 DQ893360 ABM84286 DQ894521 ABM85447 DQ896679 ABM87678 XM_005259873 XP_005259930 XM_005259874 XP_005259931 XM_005259876 XP_005259933 XM_005259877 XP_005259934 XM_011527943 XP_011526245 XM_011527944 XP_011526246 XM_011527945 XP_011526247 XM_011527946 XP_011526248 XM_011527947 XP_011526249 NM_001100176 NP_001093646 NM_013312 NP_037444
Function Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. {ECO:0000269|PubMed:17140400, ECO:0000269|PubMed:17540036, ECO:0000269|PubMed:18799622}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with aggresomes, which are aggregates of misfolded proteins, at the centrosome. Also localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.

HOOK2 (E-3) - sc-374169 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK2 (E-3): sc-374169. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

HOOK2 (E-4) - sc-137107 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK2 (E-4): sc-137107. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

HOOK2 (G-4) - sc-365716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK2 (G-4): sc-365716. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

HOOK2 (H-80) - sc-98430 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HOOK2 (H-80): sc-98430. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-172802 (B) 293T whole cell lysates.

HOOK2 (M-19) - sc-49979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HOOK2 (M-19): sc-49979. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and mouse HOOK2 transfected: sc-120876 (B) 293T whole cell lysates.

HOOK2 (T-20) - sc-49980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HOOK2 (T-20): sc-49980. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

HOOK2 (D-11) - sc-166509 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK2 (D-11): sc-166509. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

HOOK2 (C-20) - sc-49976 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HOOK2 (C-20): sc-49976. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

HOOK2 (A-8) - sc-137108 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HOOK2 (A-8): sc-137108. Western blot analysis of HOOK2 expression in non-transfected: sc-117752 (A) and human HOOK2 transfected: sc-112980 (B) 293T whole cell lysates.

Anti-HOOK2 antibody - ab89696 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HOOK2 antibody (ab89696) at 1 µg/ml + Brain (Human) Tissue Lysate - adult normal tissue (ab29466) at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-HOOK2 antibody - ab57108 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57108 HOOK2 antibody at 1ug/ml.

Anti-HOOK2 antibody [EPR8673] - ab133691 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8673
Immunohistochemical analysis of paraffin-embedded Human esophageal carcinoma tissue labelling HOOK2 with ab133691 at 1/100 dilution.

Anti-HOOK2 Antibody - LS-C178414 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HOOK2 Antibody (aa295-344) - LS-C151313 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HOOK2 antibody Western Blot of Rat Brain.

Anti-HOOK2 Antibody (Internal) - LS-C345518 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of HOOK2 Antibody with human Fetal Liver lysate.

Anti-HOOK2 Antibody (Internal, clone EPR8673) IHC-plus™ - LS-B10029 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8673
Anti-HOOK2 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-HOOK2 Antibody (aa138-238) - LS-C308283 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

HOOK2 Antibody - NBP2-14986 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HOOK2 Antibody [NBP2-14986] - Sample (30 ug of whole cell lysate) A: HCT116 7. 5% SDS PAGE; antibody diluted at 1:1000.

HOOK2 Antibody - H00029911-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

HOOK2 Antibody (1E10) - H00029911-M03 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E10

Anti-HOOK2 (171-185) antibody produced in rabbit - SAB1105084 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK2 (646-657) antibody produced in rabbit - SAB1105085 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HOOK2 antibody produced in rabbit - HPA050351 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HOOK2: <B>Cat. No. HPA050351</B>: Immunohistochemical staining of human duodenum shows strong luminal membranous and cytoplasmic positivity in glandular cells.

Anti-HOOK2 antibody produced in rabbit - HPA043519 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HOOK2: <B>Cat. No. HPA043519</B>: Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells.

Anti-HOOK2 antibody produced in rabbit - SAB2700531 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HOOK2: <B>Cat. No. SAB2700531</B>: Immunohistochemical analysis of paraffin-embedded MCF7 xenograft, using HOOK2 antibody at 1:100 dilution.
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