HOOK2

Gene Symbol	HOOK2
Entrez Gene	29911
Alt Symbol	HK2
Species	Human
Gene Type	protein-coding
Description	hook microtubule-tethering protein 2
Other Description	h-hook2|hHK2|hook homolog 2|protein Hook homolog 2
Swissprots	Q96ED9 O60562
Accessions	EAW84305 EAW84306 Q96ED9 AF044924 AAC09299 AK129729 BAC85229 BC012443 AAH12443 DB474423 DQ891339 ABM82265 DQ893360 ABM84286 DQ894521 ABM85447 DQ896679 ABM87678 XM_005259873 XP_005259930 XM_005259874 XP_005259931 XM_005259876 XP_005259933 XM_005259877 XP_005259934 XM_011527943 XP_011526245 XM_011527944 XP_011526246 XM_011527945 XP_011526247 XM_011527946 XP_011526248 XM_011527947 XP_011526249 NM_001100176 NP_001093646 NM_013312 NP_037444
Function	Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. {ECO:0000269|PubMed:17140400, ECO:0000269|PubMed:17540036, ECO:0000269|PubMed:18799622}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with aggresomes, which are aggregates of misfolded proteins, at the centrosome. Also localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HOOK2 protein (His-DHFR tag) - ab127673 from Abcam Category Protein Prices $364.00 Sizes 50 µg Source E. coli Species Human

Mouse HOOK2 peptide - ab101733 from Abcam Category Peptide

HOOK2 Antibody Blocking Peptide - LS-E19813 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HOOK2 Protein - H00029911-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Recombinant Human HOOK2 Protein - H00029911-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

HOOK2 - H00029911-P01-02 from Acris Antibodies Category Protein Prices $300.00 Sizes 2 µg Source in vitro transl. Species Human

HOOK2 - H00029911-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HOOK2 - H00029911-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HOOK2 fusion protein - Ag3124 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

HOOK2 fusion protein - Ag17417 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human HOOK2, GST-tagged - HOOK2-13883H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Protein Hook homolog 2(HOOK2) - CSB-YP839313HU CSB-EP839313HU CSB-BP839313HU CSB-MP839313HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HOOK2 Protein - abx163137 from Abbexa Category Protein Species Human

HOOK2 (transcript variant 1) - TP301913 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

HOOK2 Recombinant Protein Antigen - NBP2-47430PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HOOK2 Recombinant Protein Antigen - NBP2-47429PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HOOK2-Blocking-Peptide-N-term - BP21495a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HOOK2 Peptide, Human - M34GP07177H from Creative Peptides Category Peptide Source Synthetic. Species Human

Protein Hook homolog 2 (HOOK2), Recombinant Protein - MBS1368223 from MyBioSource Category Protein Prices $1,530.00, $1,530.00, $1,755.00, $1,755.00, $2,620.00, $2,620.00, $3,065.00, $3,065.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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