HOOK2

Gene Symbol HOOK2
Entrez Gene 29911
Alt Symbol HK2
Species Human
Gene Type protein-coding
Description hook microtubule-tethering protein 2
Other Description h-hook2|hHK2|hook homolog 2|protein Hook homolog 2
Swissprots Q96ED9 O60562
Accessions EAW84305 EAW84306 Q96ED9 AF044924 AAC09299 AK129729 BAC85229 BC012443 AAH12443 DB474423 DQ891339 ABM82265 DQ893360 ABM84286 DQ894521 ABM85447 DQ896679 ABM87678 XM_005259873 XP_005259930 XM_005259874 XP_005259931 XM_005259876 XP_005259933 XM_005259877 XP_005259934 XM_011527943 XP_011526245 XM_011527944 XP_011526246 XM_011527945 XP_011526247 XM_011527946 XP_011526248 XM_011527947 XP_011526249 NM_001100176 NP_001093646 NM_013312 NP_037444
Function Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Contributes to the establishment and maintenance of centrosome function. May function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. {ECO:0000269|PubMed:17140400, ECO:0000269|PubMed:17540036, ECO:0000269|PubMed:18799622}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with aggresomes, which are aggregates of misfolded proteins, at the centrosome. Also localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.

HOOK2 CRISPR/Cas9 KO Plasmid (h) - sc-407897 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 HDR Plasmid (h) - sc-407897-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 Double Nickase Plasmid (h) - sc-407897-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 Double Nickase Plasmid (h2) - sc-407897-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 CRISPR Activation Plasmid (h) - sc-407897-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 CRISPR Activation Plasmid (h2) - sc-407897-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 Lentiviral Activation Particles (h) - sc-407897-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 Lentiviral Activation Particles (h2) - sc-407897-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HOOK2 siRNA (h) - sc-60798 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HOOK2 shRNA Plasmid (h) - sc-60798-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HOOK2 shRNA (h) Lentiviral Particles - sc-60798-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HOOK2 RNAi - H00029911-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU137781 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10222 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10222 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HOOK2 siRNA (Human) - CRH9263 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HOOK2 RNAi - H00029911-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

HOOK2 - MBS828195 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HOOK2 (NM_013312.2) - SHH314009 from Creative biogene

Category siRNA
Species Reactivities Human

Human HOOK2 siRNA - orb269765 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HOOK2 shRNA Plasmid (Human) - CHH9263 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HOOK2 miRNA 3'UTR clone - MiUTR1H-04646 from Creative biogene

Species Reactivities Human

HOOK2 miRNA 3'UTR clone - MiUTR3H-09495 from Creative biogene

Species Reactivities Human
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