SF3B2

Gene Symbol SF3B2
Entrez Gene 10992
Alt Symbol Cus1, SAP145, SF3B145, SF3b1, SF3b150
Species Human
Gene Type protein-coding
Description splicing factor 3b, subunit 2, 145kDa
Other Description SAP 145|pre-mRNA splicing factor SF3b 145 kDa subunit|pre-mRNA-splicing factor SF3b 145 kDa subunit|spliceosome associated protein 145|spliceosome-associated protein 145|splicing factor 3B subunit 2|splicing factor 3b, subunit 2, 145kD
Swissprots Q7Z627 Q9BWD2 Q13435 B4DT19 A8K485 Q96CM6 Q969K1 Q7L4T5
Accessions EAW74491 EAW74492 EAW74493 EAW74494 EAW74495 EAW74496 EAW74497 EAW74498 EAW74499 EAW74500 EAW74501 Q13435 AK092510 AK126488 AK290850 BAF83539 AK300016 BAG61831 BC000401 AAH00401 BC007610 AAH07610 BC014125 AAH14125 BC051237 BC053577 AAH53577 BE677116 BF311442 BX537771 CAD97834 JF432116 ADZ15333 U41371 AAA97461 XM_005273726 XP_005273783 XM_011544740 XP_011543042 NM_006842 NP_006833
Function Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways Spliceosome

SAP 145 (A-20) - sc-14279 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SAP 145 (A-20): sc-14279. Indirect, intracellular FCM analysis of fixed and permeabilized Jurkat cells stained with SAP 145 (A-20), followed by FITC-conjugated donkey anti-goat IgG: sc-2024. Black line histogram represents the isotype control, normal goat IgG: sc-3887.

SAP 145 (N-20) - sc-14277 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
SAP 145 (N-20): sc-14277. Western blot analysis of SAP 145 expression in Jurkat nuclear extract.

SAP 145 (RR-30) - sc-101133 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
SAP 145 (RR-30): sc-101133. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing nuclear localization.

Anti-SF3B2 antibody - ab56800 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
SF3B2 antibody (ab56800) used in immunohistochemistry at 6ug/ml on formalin fixed and paraffin embedded human kidney.

Anti-SF3B2 antibody - ab77154 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-SF3B2 antibody (ab77154) at 1 µg/ml + Recombinant tagged full length human SF3B2 protein at 0.1 µgSecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

Anti-SF3B2 Antibody (aa1-636) - LS-C132002 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545, AP) - LS-C269085 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545, APC) - LS-C269086 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545, Biotin) - LS-C269087 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545, FITC) - LS-C269088 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545, Azide-free, HRP) - LS-C269089 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545, PE) - LS-C269090 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa515-545) - LS-C325031 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SF3B2 Antibody (aa592-646, Azide-free) - LS-C328597 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SF3B2 Antibody (aa539-568) - LS-C169007 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SF3B2 Antibody western blot of A549 cell line lysates (35 ug/lane). The SF3B2 antibody detected the SF3B2 protein (arrow).

Anti-SF3B2 Antibody (aa825-872) - LS-C288396 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SF3b145/SAP145 by Immunohistochemistry. Sample: FFPE section of human linitis plastica stomach cancer. Antibody: Affinity purified rabbit anti-SF3b145/SAP145 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-SF3B2 Antibody (aa775-825) - LS-C288395 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SF3b145/SAP145 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-SF3b145/SAP145 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-SF3B2 Antibody - LS-C334356 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using SF3B2 antibody.

Anti-SF3B2 Antibody (aa775-825) - LS-C286555 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SF3b145/SAP145 by IHC-IF. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-SF3b145/SAP145 used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.

Anti-SF3B2 Antibody (clone 5D2) - LS-C133670 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5D2
Immunoperoxidase of monoclonal antibody to SF3B2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 6 ug/ml]

SF3B2 Antibody (5D2) - H00010992-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5D2
Western Blot: SF3B2 Antibody (5D2) [H00010992-M01] - SF3B2 monoclonal antibody (M01), clone 5D2 Analysis of SF3B2 expression in Hela S3 NE.

SF3B2 Antibody - NB100-79847 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SF3B2 Antibody [NB100-79847] - Detection of Human SF3b145/SAP145 on HeLa whole cell lysate using NB100-79847. SF3b145/SAP145 was also immunoprecipitated by rabbit anti-SF3b145/SAP145 antibody NB100-79848.

SF3B2 Antibody - NB100-79848 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SF3B2 Antibody [NB100-79848] - Detection of Human SF3b145/SAP145 on HeLa whole cell lysate using NB100-79848. SF3b145/SAP145 was also immunoprecipitated by rabbit anti-SF3b145/SAP145 antibody NB100-79847.

SF3B2 Antibody - H00010992-B01 from Novus Biologicals

Host Mouse
Clonality Polyclonal
Western Blot: SF3B2 Antibody [H00010992-B01] - analysis of SF3B2 expression in transfected 293T cell line by SF3B2 MaxPab polyclonal antibody (B01). Lane 1: SF3B2 transfected lysate (72.60 KDa). Lane 2: Non-transfected lysate.

SF3B2 Antibody - NBP1-92380 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: SF3B2 Antibody [NBP1-92380] - Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles.
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