SF3B2

Gene Symbol SF3B2
Entrez Gene 10992
Alt Symbol Cus1, SAP145, SF3B145, SF3b1, SF3b150
Species Human
Gene Type protein-coding
Description splicing factor 3b, subunit 2, 145kDa
Other Description SAP 145|pre-mRNA splicing factor SF3b 145 kDa subunit|pre-mRNA-splicing factor SF3b 145 kDa subunit|spliceosome associated protein 145|spliceosome-associated protein 145|splicing factor 3B subunit 2|splicing factor 3b, subunit 2, 145kD
Swissprots Q7Z627 Q9BWD2 Q13435 B4DT19 A8K485 Q96CM6 Q969K1 Q7L4T5
Accessions EAW74491 EAW74492 EAW74493 EAW74494 EAW74495 EAW74496 EAW74497 EAW74498 EAW74499 EAW74500 EAW74501 Q13435 AK092510 AK126488 AK290850 BAF83539 AK300016 BAG61831 BC000401 AAH00401 BC007610 AAH07610 BC014125 AAH14125 BC051237 BC053577 AAH53577 BE677116 BF311442 BX537771 CAD97834 JF432116 ADZ15333 U41371 AAA97461 XM_005273726 XP_005273783 XM_011544740 XP_011543042 NM_006842 NP_006833
Function Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways Spliceosome

SAP 145 CRISPR/Cas9 KO Plasmid (h) - sc-403214 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 HDR Plasmid (h) - sc-403214-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 Double Nickase Plasmid (h) - sc-403214-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 Double Nickase Plasmid (h2) - sc-403214-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 CRISPR Activation Plasmid (h) - sc-403214-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 CRISPR Activation Plasmid (h2) - sc-403214-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 Lentiviral Activation Particles (h) - sc-403214-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 Lentiviral Activation Particles (h2) - sc-403214-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SAP 145 siRNA (h) - sc-38316 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAP 145 shRNA Plasmid (h) - sc-38316-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SAP 145 shRNA (h) Lentiviral Particles - sc-38316-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SF3B2 RNAi - H00010992-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU061071 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19187 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19187 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00231 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00231

SF3B2 siRNA (Human) - CRH7507 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SF3B2 - MBS8234681 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SF3B2 (NM_006842.2) - SHH405824 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SF3B2(NM_006842.2) - SHR219354 from Creative biogene

Category siRNA
Species Reactivities Human

Human SF3B2 siRNA - orb268009 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SF3B2 shRNA Plasmid (Human) - CHH7507 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SF3B2 miRNA 3'UTR clone - MiUTR1H-09326 from Creative biogene

Species Reactivities Human
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