SF3B2

Gene Symbol	SF3B2
Entrez Gene	10992
Alt Symbol	Cus1, SAP145, SF3B145, SF3b1, SF3b150
Species	Human
Gene Type	protein-coding
Description	splicing factor 3b, subunit 2, 145kDa
Other Description	SAP 145|pre-mRNA splicing factor SF3b 145 kDa subunit|pre-mRNA-splicing factor SF3b 145 kDa subunit|spliceosome associated protein 145|spliceosome-associated protein 145|splicing factor 3B subunit 2|splicing factor 3b, subunit 2, 145kD
Swissprots	Q7Z627 Q9BWD2 Q13435 B4DT19 A8K485 Q96CM6 Q969K1 Q7L4T5
Accessions	EAW74491 EAW74492 EAW74493 EAW74494 EAW74495 EAW74496 EAW74497 EAW74498 EAW74499 EAW74500 EAW74501 Q13435 AK092510 AK126488 AK290850 BAF83539 AK300016 BAG61831 BC000401 AAH00401 BC007610 AAH07610 BC014125 AAH14125 BC051237 BC053577 AAH53577 BE677116 BF311442 BX537771 CAD97834 JF432116 ADZ15333 U41371 AAA97461 XM_005273726 XP_005273783 XM_011544740 XP_011543042 NM_006842 NP_006833
Function	Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
Subcellular Location	Nucleus {ECO:0000250}.
Top Pathways	Spliceosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SF3B2 full length protein - ab161228 from Abcam Category Protein Source Wheat germ Species Human

Human SF3B2 protein fragment - ab161229 from Abcam Category Protein Source Wheat germ Species Human

SF3B2 Antibody Blocking Peptide - LS-E3982 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SF3B2 Recombinant Protein - H00010992-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human SF3B2 Protein - H00010992-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SF3B2-Antibody-Center-Blocking-Peptide - BP16199c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SF3B2 / SAP145 - H00010992-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SF3B2 / SAP145 - H00010992-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SF3B2 / SAP145 - H00010992-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SF3B2 / SAP145 - H00010992-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SF3B2 fusion protein - ag1009 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Splicing factor 3B subunit 2(SF3B2) ,partial - CSB-YP615687HU CSB-EP615687HU CSB-BP615687HU CSB-MP615687HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Splicing factor 3b, subunit 2, 145kDa (SF3B2) - TP322762 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SF3B2 Recombinant Protein Antigen - NBP1-92380PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SF3B2 Peptide, Human - M34GP14100H from Creative Peptides Category Peptide Source Synthetic. Species Human

Splicing factor 3B subunit 2 (SF3B2), partial, Recombinant Protein - MBS1300983 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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