| Gene Symbol |
SHROOM2
|
| Entrez Gene |
357
|
| Alt Symbol |
APXL, HSAPXL
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
shroom family member 2
|
| Other Description |
APX homolog of Xenopus|apical-like protein|protein Shroom2
|
| Swissprots |
Q13796 B9EIQ7
|
| Accessions |
AAC32592 EAW98774 Q13796 AK096596 BAG53335 AK299907 BAH13168 BC140866 AAI40867 CR749271 CAH18127 X83543 CAA58534 XM_005274500 XP_005274557 XM_011545506 XP_011543808 NM_001649 NP_001640
|
| Function |
May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Apical cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associates with cortical F-actin. {ECO:0000250}.
|
| Tissue Specificity |
Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.
|
| Top Pathways |
Tight junction
|