Gene Symbol | SHROOM2 |
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Entrez Gene | 357 |
Alt Symbol | APXL, HSAPXL |
Species | Human |
Gene Type | protein-coding |
Description | shroom family member 2 |
Other Description | APX homolog of Xenopus|apical-like protein|protein Shroom2 |
Swissprots | Q13796 B9EIQ7 |
Accessions | AAC32592 EAW98774 Q13796 AK096596 BAG53335 AK299907 BAH13168 BC140866 AAI40867 CR749271 CAH18127 X83543 CAA58534 XM_005274500 XP_005274557 XM_011545506 XP_011543808 NM_001649 NP_001640 |
Function | May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity). {ECO:0000250}. |
Subcellular Location | Apical cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associates with cortical F-actin. {ECO:0000250}. |
Tissue Specificity | Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas. |
Top Pathways | Tight junction |
APXL (N-18) - sc-70114 from Santa Cruz Biotechnology
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APXL (S-18) - sc-70116 from Santa Cruz Biotechnology
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Anti-APXL antibody - ab85078 from Abcam
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Anti-APXL antibody - ab173510 from Abcam
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Anti-APXL antibody - ab86265 from Abcam
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Anti-APXL antibody - C-terminal - ab137445 from Abcam
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Anti-SHROOM2 Antibody IHC-plus⢠- LS-B4070 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625, AP) - LS-C269394 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625, APC) - LS-C269395 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625, Biotin) - LS-C269396 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625, FITC) - LS-C269397 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625, Azide-free, HRP) - LS-C269398 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa1295-1344) - LS-C101529 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625, PE) - LS-C269399 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa598-625) - LS-C325113 from LifeSpan Bioscience
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Anti-SHROOM2 Antibody (aa599-625) - LS-C158967 from LifeSpan Bioscience
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APXL Antibody - NBP2-15437 from Novus Biologicals
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APXL Antibody - NBP1-52251 from Novus Biologicals
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APXL Antibody - NBP2-13308 from Novus Biologicals
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APXL Antibody - NB100-1350 from Novus Biologicals
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APXL Polyclonal Antibody - bs-12131R from Bioss
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APXL Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12131R-A350 from Bioss
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APXL Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12131R-A488 from Bioss
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APXL Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12131R-A555 from Bioss
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APXL Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12131R-A647 from Bioss
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