SHROOM2
| Gene Symbol | SHROOM2 |
|---|---|
| Entrez Gene | 357 |
| Alt Symbol | APXL, HSAPXL |
| Species | Human |
| Gene Type | protein-coding |
| Description | shroom family member 2 |
| Other Description | APX homolog of Xenopus|apical-like protein|protein Shroom2 |
| Swissprots | Q13796 B9EIQ7 |
| Accessions | AAC32592 EAW98774 Q13796 AK096596 BAG53335 AK299907 BAH13168 BC140866 AAI40867 CR749271 CAH18127 X83543 CAA58534 XM_005274500 XP_005274557 XM_011545506 XP_011543808 NM_001649 NP_001640 |
| Function | May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity). {ECO:0000250}. |
| Subcellular Location | Apical cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associates with cortical F-actin. {ECO:0000250}. |
| Tissue Specificity | Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas. |
| Top Pathways | Tight junction |
Human APXL peptide - ab23127 from Abcam
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SHROOM2 Antibody Blocking Peptide - LS-E5342 from LifeSpan Bioscience
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SHROOM2-Antibody-Center-Blocking-Peptide - BP17830c from Abgent, a WuXi AppTec company
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APXL blocking peptide - GTX25948-PEP from GeneTex
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SHROOM2 Blocking Peptide - 33R-1824 from Fitzgerald
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SHROOM2 fusion protein - Ag24387 from Proteintech Group
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Recombinant Human Protein Shroom2(SHROOM2) ,partial - CSB-YP622684HU CSB-EP622684HU CSB-BP622684HU CSB-MP622684HU from Cusabio
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APXL, Peptide - MBS428516 from MyBioSource
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APXL Recombinant Protein Antigen - NBP2-13308PEP from Novus Biologicals
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SHROOM2 Peptide, Human - M34GP14226H from Creative Peptides
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Protein Shroom2 (SHROOM2), partial, Recombinant Protein - MBS1324679 from MyBioSource
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