LTK
| Gene Symbol | LTK |
|---|---|
| Entrez Gene | 4058 |
| Alt Symbol | TYK1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | leukocyte receptor tyrosine kinase |
| Other Description | leukocyte tyrosine kinase receptor|protein tyrosine kinase 1 |
| Swissprots | A6NNJ8 B4DL89 E9PFX4 P29376 |
| Accessions | CAM91186 EAW92494 EAW92495 EAW92496 EAW92497 EAW92498 EAW92499 EAW92500 EAW92501 P29376 AK296892 BAG59451 AK314006 BC045607 AAH45607 BC143903 BX329448 CA394397 D16105 BAA03679 DA452723 DB331746 X52213 CAA36460 X60702 CAA43113 XM_011521556 XP_011519858 XM_011521557 XP_011519859 XM_011521558 XP_011519860 NM_001135685 NP_001129157 NM_002344 NP_002335 NM_206961 NP_996844 |
| Function | Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport. {ECO:0000269|PubMed:20548102}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed in non-hematopoietic cell lines and T- and B-cell lines. {ECO:0000269|PubMed:2156206}. |
LTK (B-6) - sc-393465 from Santa Cruz Biotechnology
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LTK (H-74) - sc-367583 from Santa Cruz Biotechnology
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LTK (N-18) - sc-6350 from Santa Cruz Biotechnology
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Anti-LTK antibody - ab115273 from Abcam
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Anti-LTK antibody - ab5507 from Abcam
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Anti-LTK antibody - ab47072 from Abcam
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Anti-LTK antibody [EPR5175(2)] - ab129155 from Abcam
![All lanes : Anti-LTK antibody [EPR5175(2)] (ab129155) at 1/1000 dilutionLane 1 : Raji cell lysateLane 2 : Human tonsil lysateLane 3 : Human spleen lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution](http://www.bioprodhub.com/system/product_images/ab_products/2/sub_3/17795_LTK-Primary-antibodies-ab129155-1.JPG)
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Anti-LTK Antibody (aa10-424) - LS-C182903 from LifeSpan Bioscience
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Anti-LTK Antibody (aa233-282) - LS-C135760 from LifeSpan Bioscience
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Anti-LTK Antibody (Arg241) - LS-C192008 from LifeSpan Bioscience
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Anti-LTK Antibody (aa794-822, AP) - LS-C262348 from LifeSpan Bioscience
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Anti-LTK Antibody (Internal) - LS-C210142 from LifeSpan Bioscience
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Anti-LTK Antibody (aa794-822, APC) - LS-C262349 from LifeSpan Bioscience
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Anti-LTK Antibody (aa794-822, Biotin) - LS-C262351 from LifeSpan Bioscience
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Anti-LTK Antibody (aa794-822, FITC) - LS-C262352 from LifeSpan Bioscience
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Anti-LTK Antibody (aa42-72) - LS-C97565 from LifeSpan Bioscience
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Anti-LTK Antibody (aa794-822, Azide-free, HRP) - LS-C262353 from LifeSpan Bioscience
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Anti-LTK Antibody (aa794-822, PE) - LS-C262355 from LifeSpan Bioscience
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Anti-LTK Antibody (N-Terminus, AP) - LS-C279003 from LifeSpan Bioscience
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Anti-LTK Antibody (aa795-822) - LS-C164440 from LifeSpan Bioscience
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Anti-LTK Antibody (N-Terminus, APC) - LS-C279004 from LifeSpan Bioscience
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Anti-LTK Antibody (C-Terminus, clone EPR5175(2)) - LS-C154437 from LifeSpan Bioscience
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Anti-LTK Antibody (N-Terminus, Azide-free, HRP) - LS-C279006 from LifeSpan Bioscience
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Anti-LTK Antibody (N-Terminus, Biotin) - LS-C279005 from LifeSpan Bioscience
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Anti-LTK Antibody (N-Terminus, FITC) - LS-C279007 from LifeSpan Bioscience
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