LTK

Gene Symbol	LTK
Entrez Gene	4058
Alt Symbol	TYK1
Species	Human
Gene Type	protein-coding
Description	leukocyte receptor tyrosine kinase
Other Description	leukocyte tyrosine kinase receptor|protein tyrosine kinase 1
Swissprots	A6NNJ8 B4DL89 E9PFX4 P29376
Accessions	CAM91186 EAW92494 EAW92495 EAW92496 EAW92497 EAW92498 EAW92499 EAW92500 EAW92501 P29376 AK296892 BAG59451 AK314006 BC045607 AAH45607 BC143903 BX329448 CA394397 D16105 BAA03679 DA452723 DB331746 X52213 CAA36460 X60702 CAA43113 XM_011521556 XP_011519858 XM_011521557 XP_011519859 XM_011521558 XP_011519860 NM_001135685 NP_001129157 NM_002344 NP_002335 NM_206961 NP_996844
Function	Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport. {ECO:0000269|PubMed:20548102}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in non-hematopoietic cell lines and T- and B-cell lines. {ECO:0000269|PubMed:2156206}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LTK CRISPR/Cas9 KO Plasmid (h) - sc-405150 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK HDR Plasmid (h) - sc-405150-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK Double Nickase Plasmid (h) - sc-405150-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK Double Nickase Plasmid (h2) - sc-405150-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK CRISPR Activation Plasmid (h) - sc-405150-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK CRISPR Activation Plasmid (h2) - sc-405150-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK Lentiviral Activation Particles (h) - sc-405150-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK Lentiviral Activation Particles (h2) - sc-405150-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

LTK siRNA (h) - sc-40085 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LTK shRNA Plasmid (h) - sc-40085-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LTK shRNA (h) Lentiviral Particles - sc-40085-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

LTK RNAi - H00004058-R07 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU161121 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1079 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1081 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1080 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN12822 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12822 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02642 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02642

LTK siRNA (Human) - CRH2747 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LTK RNAi - H00004058-R08 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human LTK (NM_002344.5) - SHH335547 from Creative biogene Category siRNA Species Reactivities Human

Human LTK siRNA - orb263249 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

LTK shRNA Plasmid (Human) - CHH2747 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

LTK miRNA 3'UTR clone - MiUTR3H-01311 from Creative biogene Species Reactivities Human

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