LTK

Gene Symbol LTK
Entrez Gene 4058
Alt Symbol TYK1
Species Human
Gene Type protein-coding
Description leukocyte receptor tyrosine kinase
Other Description leukocyte tyrosine kinase receptor|protein tyrosine kinase 1
Swissprots A6NNJ8 B4DL89 E9PFX4 P29376
Accessions CAM91186 EAW92494 EAW92495 EAW92496 EAW92497 EAW92498 EAW92499 EAW92500 EAW92501 P29376 AK296892 BAG59451 AK314006 BC045607 AAH45607 BC143903 BX329448 CA394397 D16105 BAA03679 DA452723 DB331746 X52213 CAA36460 X60702 CAA43113 XM_011521556 XP_011519858 XM_011521557 XP_011519859 XM_011521558 XP_011519860 NM_001135685 NP_001129157 NM_002344 NP_002335 NM_206961 NP_996844
Function Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport. {ECO:0000269|PubMed:20548102}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Expressed in non-hematopoietic cell lines and T- and B-cell lines. {ECO:0000269|PubMed:2156206}.

Human LTK cDNA clone(NM_001135685.1) - CDFH010783 from Creative Biomart

Species Human
Accession NM_001135685.1

Human LTK ORF Clone(NM_206961.3) - CDCR327751 from Creative Biomart

Species Human
Accession NM_206961.3

Human LTK ORF Clone(NM_206961.3) - CDCR327752 from Creative Biomart

Species Human
Accession NM_206961.3

Human LTK ORF Clone(NM_001135685.1) - CDCR350459 from Creative Biomart

Species Human
Accession NM_001135685.1

Human LTK ORF Clone(NM_001135685.1) - CDCR350461 from Creative Biomart

Species Human
Accession NM_001135685.1

Human LTK Gene cDNA Clone (full-length ORF Clone) - HG16063-G from Sino Biological

Species Human
Accession NM_002344.5

Human LTK natural ORF mammalian expression plasmid, N-Flag tag - HG16063-NF from Sino Biological

Species Human
Accession NM_002344.5

Human LTK natural ORF mammalian expression plasmid, C-OFPSpark tag - HG16063-ACR from Sino Biological

Species Human
Accession NM_002344.5

Human LTK natural ORF mammalian expression plasmid, N-Myc tag - HG16063-NM from Sino Biological

Species Human
Accession NM_002344.5

Human LTK ORF Clone(NM_206961.3) - CDCR327751 from Creative biogene

Species Human

Mouse LTK ORF clone (NM_001135685.1) - CDCL129247 from Creative biogene

Species Human

Mouse LTK ORF clone (NM_002344.5) - CDCL129249 from Creative biogene

Species Human

Human LTK cDNA Clone(NM_001135685.1) - CDFH010783 from Creative biogene

Species Human
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