Gene Symbol | NOX1 |
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Entrez Gene | 27035 |
Alt Symbol | GP91-2, MOX1, NOH-1, NOH1 |
Species | Human |
Gene Type | protein-coding |
Description | NADPH oxidase 1 |
Other Description | NADH/NADPH mitogenic oxidase subunit P65-MOX|NADPH oxidase homolog-1|mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating)|mitogenic oxidase 1 |
Swissprots | Q2PP02 O95691 Q9Y5S8 A8K836 |
Accessions | ABC40742 EAX02820 EAX02821 EAX02822 EAX02823 EAX02824 Q9Y5S8 AF127763 AAD38133 AF166326 AAF23232 AF166327 AAF23233 AF166328 AAF23234 AI285296 AJ438989 CAD27735 AK292201 BAF84890 AK313678 BC075014 AAH75014 BC075015 AAH75015 BX956931 DQ424904 ABD83669 NM_001271815 NP_001258744 NM_007052 NP_008983 NM_013955 NP_039249 NM_013954 |
Function | NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. |
Subcellular Location | Cell projection, invadopodium membrane {ECO:0000269|PubMed:19755710}; Multi-pass membrane protein {ECO:0000269|PubMed:19755710}. |
Tissue Specificity | NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH- 1S is detected only in colon and colon carcinoma cells. |
Top Pathways | Leukocyte transendothelial migration, Phagosome, Osteoclast differentiation |
NOX1 peptide - ab194192 from Abcam
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NOX1 Antibody Blocking Peptide - LS-E4811 from LifeSpan Bioscience
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NOX1 Antibody Blocking Peptide - LS-E27560 from LifeSpan Bioscience
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NOX1-Antibody-Center-Blocking-Peptide - BP17191c from Abgent, a WuXi AppTec company
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MOX1 Peptide - GTX84998-PEP from GeneTex
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NOX1 Blocking Peptide - 33R-8868 from Fitzgerald
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Human NOX1 Protein - abx068290 from Abbexa
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NOX1 Peptide - AC21-2382-P from Abcore
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Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1), Human - 20-6788 from ARP American Research Products
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NOX1 Peptide - 42-316P from ProSci
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NOX1 Peptide - 7921P from ProSci
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NOX1 fusion protein - Ag12410 from Proteintech Group
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NOX1 fusion protein - ag12187 from Proteintech Group
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Recombinant Human NOX1, His-tagged - NOX1-1335H from Creative Biomart
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Recombinant Human NOX1 - NOX1-404H from Creative Biomart
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Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) - RPA554Hu01 from Uscn Life Science Inc.
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Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) - RPA554Ra01 from Uscn Life Science Inc.
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Recombinant Cluster Of Differentiation 200 (CD200) - RPA880Hu01 from Cloud-clone
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Recombinant Nicotinamide Adenine Dinucleotide Phosphate Oxidase 1 (NOX1) - RPA554Hu01 from Cloud-clone
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NOX1, Peptide - MBS427730 from MyBioSource
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NOX1 Protein - NBP1-83347PEP from Novus Biologicals
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NOX1 Protein - NBP1-83346PEP from Novus Biologicals
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NOX1 Peptide, Human - M34GP10524H from Creative Peptides
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NOX1 Blocking Peptide - CBP5425 from Cohesion Biosciences
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NOX1 peptide - orb374849 from Biorbyt
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