NOX1

Gene Symbol NOX1
Entrez Gene 27035
Alt Symbol GP91-2, MOX1, NOH-1, NOH1
Species Human
Gene Type protein-coding
Description NADPH oxidase 1
Other Description NADH/NADPH mitogenic oxidase subunit P65-MOX|NADPH oxidase homolog-1|mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating)|mitogenic oxidase 1
Swissprots Q2PP02 O95691 Q9Y5S8 A8K836
Accessions ABC40742 EAX02820 EAX02821 EAX02822 EAX02823 EAX02824 Q9Y5S8 AF127763 AAD38133 AF166326 AAF23232 AF166327 AAF23233 AF166328 AAF23234 AI285296 AJ438989 CAD27735 AK292201 BAF84890 AK313678 BC075014 AAH75014 BC075015 AAH75015 BX956931 DQ424904 ABD83669 NM_001271815 NP_001258744 NM_007052 NP_008983 NM_013955 NP_039249 NM_013954
Function NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
Subcellular Location Cell projection, invadopodium membrane {ECO:0000269|PubMed:19755710}; Multi-pass membrane protein {ECO:0000269|PubMed:19755710}.
Tissue Specificity NOH-1L is detected in colon, uterus, prostate, and colon carcinoma, but not in peripheral blood leukocytes. NOH- 1S is detected only in colon and colon carcinoma cells.
Top Pathways Leukocyte transendothelial migration, Phagosome, Osteoclast differentiation

Mox1 (H-75) - sc-25545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Mox1 (H-75): sc-25545. Western blot analysis of human recombinant Mox1.

Mox1 (N-15) - sc-5819 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Mox1 (H-15) - sc-5821 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NOX1 antibody - ab55831 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab55831 stained HepG2 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab55831, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-NOX1 antibody - ab78016 from Abcam

Prices $379.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab78016, at 10µg/ml, staining NOX1 in Human colon by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

Anti-NOX1 antibody - ab137603 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-NOX1 antibody (ab137603) at 1/5000 dilutionLane 1 : JC whole cell lysateLane 2 : BCL-1 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-NOX1 antibody - ab101027 from Abcam

Prices $376.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NOX1 antibody (ab101027) at 1/250 dilutionLane 1 : DU 145 (Human prostate carcinoma cell line) Whole Cell LysateLane 2 : PC3 (Human prostate cancer cell line) Whole Cell Lysate (ab3954)Lane 3 : LNCaP human prostate carcinoma cell line lysate Whole Cell LysateLane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 5 : Caco 2 (Human colonic carcinoma cell line) Whole Cell LysateLane 6 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-NOX1 antibody - ab130478 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-NOX1 antibody (ab130478) at 1/100 dilution + WiDr cell line lysate at 35 µg

Anti-NOX1 Antibody (aa235-488, FITC) - LS-C301444 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa242-271) - LS-C323401 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa417-431) - LS-C312820 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of NOX1 antibody. Lane 1: Rat Heart Tissue Lysate. Lane 2: Rat Brain Tissue Lysate. Lane 3: Mouse Heart Tissue Lysate. Lane 4: Mouse Heart Tissue Lysate ..

Anti-NOX1 Antibody (C-Terminus) - LS-C80939 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane A: Marker. Lane B: Jurkat cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-NOX1 Antibody (aa235-488) - LS-C295626 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant NOX1.

Anti-NOX1 Antibody (aa243-271) - LS-C158413 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NOX1 Antibody western blot of WiDr cell line lysates (35 ug/lane). The NOX1 antibody detected the NOX1 protein (arrow).

Anti-NOX1 Antibody (aa354-374) - LS-C312889 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
NOX1 antibody. IHC(P): Human Lung Cancer Tissue.

Anti-NOX1 Antibody (C-Terminus) IHC-plus™ - LS-B1832 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-NOX1 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1832 concentration 10 ug/ml.

Anti-NOX1 Antibody (Internal) - LS-C336196 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of NOX1 in human kidney tissue with NOX1 antibody at 5 ug/ml.

Anti-NOX1 Antibody (aa490-502) IHC-plus™ - LS-B11179 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-NOX1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11179 concentration 5 ug/ml.

Anti-NOX1 Antibody (aa243-271, APC) - LS-C216015 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa243-271, AP) - LS-C216014 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa243-271, Biotin) - LS-C216016 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa243-271, Azide-free, HRP) - LS-C216017 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa243-271, FITC) - LS-C216018 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa243-271, PE) - LS-C216019 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NOX1 Antibody (aa436-485) - LS-C291350 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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