Gene Symbol | TTF2 |
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Entrez Gene | 8458 |
Alt Symbol | HuF2, ZGRF6 |
Species | Human |
Gene Type | protein-coding |
Description | transcription termination factor, RNA polymerase II |
Other Description | F2|RNA polymerase II termination factor|human factor 2|lodestar homolog|lodestar protein|transcription release factor 2|transcription termination factor 2|zinc finger, GRF-type containing 6 |
Swissprots | Q9UNY4 O75921 Q8N6I8 Q5VVU8 Q5T2K7 A8K4Q2 |
Accessions | EAW56666 EAW56667 Q9UNY4 AB209845 BAD93082 AF073771 AAC64044 AF080255 AAD49435 AI991355 AK291017 BAF83706 AW027795 BC015341 BC030058 AAH30058 BI857056 BQ422564 BU182600 H81916 XM_005271277 XP_005271334 XM_006710979 XP_006711042 XM_006710980 XP_006711043 XM_006710981 XP_006711044 XM_011542303 XP_011540605 XM_011542304 XP_011540606 XM_011542305 XP_011540607 XR_946782 NM_003594 NP_003585 |
Function | DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing. {ECO:0000269|PubMed:10455150, ECO:0000269|PubMed:12927788, ECO:0000269|PubMed:15125840, ECO:0000269|PubMed:9748214}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15125840}. Nucleus {ECO:0000269|PubMed:15125840}. Note=Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis. |
Top Pathways | Thyroid hormone synthesis |
Active human Thrombin full length protein - ab62452 from Abcam
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Human Thrombin peptide - ab102604 from Abcam
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Human TTF2 protein fragment - ab160040 from Abcam
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F2 / Prothrombin / Thrombin Antibody Blocking Peptide - LS-E15364 from LifeSpan Bioscience
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F2 / Prothrombin / Thrombin Blocking Peptide - LS-E15365 from LifeSpan Bioscience
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Prothrombin Partial Recombinant Protein - H00002147-Q01 from Novus Biologicals
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Prothrombin Recombinant Protein - H00002147-P01 from Novus Biologicals
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Mouse F2 His tag protein - orb84060 from Biorbyt
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F2 Blocking Peptide - 33R-1783 from Fitzgerald
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TTF2 - H00008458-Q01-10 from Acris Antibodies
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TTF2 - H00008458-Q01-25 from Acris Antibodies
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TTF2 fusion protein - Ag4671 from Proteintech Group
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Recombinant Human TTF2, GST-tagged - TTF2-3478H from Creative Biomart
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Thrombin Polypeptide - PCB-DAG428 from Nordic BioSite
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Recombinant Human Transcription termination factor 2(TTF2) ,partial - CSB-YP891793HU CSB-EP891793HU CSB-BP891793HU CSB-MP891793HU from Cusabio
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TTF2 Protein - abx163924 from Abbexa
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F2 Recombinant Protein Antigen - NBP2-33728PEP from Novus Biologicals
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F2 Recombinant Protein Antigen - NBP2-33617PEP from Novus Biologicals
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TTF2-Antibody-Center-Blocking-Peptide - BP6813c from Abgent, a WuXi AppTec company
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TTF2-Antibody-N-term-Blocking-Peptide - BP6813a from Abgent, a WuXi AppTec company
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F2 Peptide, Human - M34GP05169H from Creative Peptides
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Recombinant Human Prothrombin Protein - NBP2-51676 from Novus Biologicals
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