TTF2

Gene Symbol TTF2
Entrez Gene 8458
Alt Symbol HuF2, ZGRF6
Species Human
Gene Type protein-coding
Description transcription termination factor, RNA polymerase II
Other Description F2|RNA polymerase II termination factor|human factor 2|lodestar homolog|lodestar protein|transcription release factor 2|transcription termination factor 2|zinc finger, GRF-type containing 6
Swissprots Q9UNY4 O75921 Q8N6I8 Q5VVU8 Q5T2K7 A8K4Q2
Accessions EAW56666 EAW56667 Q9UNY4 AB209845 BAD93082 AF073771 AAC64044 AF080255 AAD49435 AI991355 AK291017 BAF83706 AW027795 BC015341 BC030058 AAH30058 BI857056 BQ422564 BU182600 H81916 XM_005271277 XP_005271334 XM_006710979 XP_006711042 XM_006710980 XP_006711043 XM_006710981 XP_006711044 XM_011542303 XP_011540605 XM_011542304 XP_011540606 XM_011542305 XP_011540607 XR_946782 NM_003594 NP_003585
Function DsDNA-dependent ATPase which acts as a transcription termination factor by coupling ATP hydrolysis with removal of RNA polymerase II from the DNA template. May contribute to mitotic transcription repression. May also be involved in pre-mRNA splicing. {ECO:0000269|PubMed:10455150, ECO:0000269|PubMed:12927788, ECO:0000269|PubMed:15125840, ECO:0000269|PubMed:9748214}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15125840}. Nucleus {ECO:0000269|PubMed:15125840}. Note=Cytoplasmic during interphase. Relocates to the nucleus as cells enter mitosis.
Top Pathways Thyroid hormone synthesis

TTF2 CRISPR/Cas9 KO Plasmid (h) - sc-409715 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 HDR Plasmid (h) - sc-409715-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 Double Nickase Plasmid (h) - sc-409715-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 Double Nickase Plasmid (h2) - sc-409715-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 CRISPR Activation Plasmid (h) - sc-409715-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 CRISPR Activation Plasmid (h2) - sc-409715-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 Lentiviral Activation Particles (h) - sc-409715-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 Lentiviral Activation Particles (h2) - sc-409715-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TTF2 siRNA (h) - sc-106890 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TTF2 shRNA Plasmid (h) - sc-106890-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TTF2 shRNA (h) Lentiviral Particles - sc-106890-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Prothrombin RNAi - H00002147-R01V from Novus Biologicals

Category siRNA
Prices $629.00
Sizes 20 nmol
Species Reactivities Human
Western blot analysis of F2 over-expressed 293 cell line, cotransfected with F2 Validated Chimera RNAi or non-transfected control. Blot probed with H00002147-M01. GAPDH (36.1 kDa) used as loading control.

Prothrombin RNAi - H00002147-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU049891 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22191 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22191 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09011 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09011

TTF2 siRNA (Human) - CRH5545 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TTF2 - MBS8225943 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TTF2 (NM_003594.3) - SHH437280 from Creative biogene

Category siRNA
Species Reactivities Human

Human TTF2 siRNA - orb266047 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TTF2 shRNA Plasmid (Human) - CHH5545 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TTF2 miRNA 3'UTR clone - MiUTR1H-10860 from Creative biogene

Species Reactivities Human
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