BANF1

Gene Symbol	BANF1
Entrez Gene	8815
Alt Symbol	BAF, BCRP1, D14S1460, NGPS
Species	Human
Gene Type	protein-coding
Description	barrier to autointegration factor 1
Other Description	barrier-to-autointegration factor|breakpoint cluster region protein 1
Swissprots	O75531 Q6FGG7 O60558
Accessions	EAW74483 EAW74484 EAW74485 EAW74486 O75531 AF044773 AAC08964 AF068235 AAD15901 AF070447 AAC23575 AK311961 BAG34901 BC005942 AAH05942 BC008705 BC107702 AAI07703 BG748852 BU940708 CR542140 CAG46937 NM_001143985 NP_001137457 NM_003860 NP_003851
Function	Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self- destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. {ECO:0000269|PubMed:11005805, ECO:0000269|PubMed:12163470, ECO:0000269|PubMed:16680152}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:16495336}. Cytoplasm {ECO:0000269|PubMed:16495336}. Chromosome {ECO:0000269|PubMed:16495336}. Note=Significantly enriched at the nuclear inner membrane, diffusely throughout the nucleus during interphase and concentrated at the chromosomes during the M-phase. May be included in HIV-1 virions via its interaction with viral GAG polyprotein. The phosphorylated form (by VRK1) shows a cytoplasmic localization.
Tissue Specificity	Widely expressed. Expressed in colon, brain, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen and testis. Not detected in thymus and peripheral blood leukocytes.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BANF1 full length protein - ab152917 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BANF1 / BAF / BCRP1 Antibody Blocking Peptide - LS-E2946 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BANF1 / BAF / BCRP1 Antibody Blocking Peptide - LS-E30300 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

BANF1 / BAF / BCRP1 Antibody Blocking Peptide - LS-E30301 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

BANF1 / BAF / BCRP1 Antibody Blocking Peptide - LS-E23429 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BANF1 Protein - H00008815-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

BANF1 Blocking Peptide - NBP1-76751PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

BANF1 Blocking Peptide - NBP1-76750PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

BANF1-Antibody-Center-Blocking-peptide - BP14071c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BANF1 - H00008815-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

BANF1 - H00008815-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

BANF1 Control Peptide - AP30118CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

BANF1 Control Peptide - AP30119CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

BANF1 Peptide - 4019P from ProSci Category Peptide Species Human

BANF1 Peptide - 4017P from ProSci Category Peptide Species Human

Recombinant Human Barrier-to-autointegration factor(BANF1) - CSB-YP002550HU CSB-EP002550HU CSB-BP002550HU CSB-MP002550HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Barrier To Autointegration Factor 1 (BANF1) - RPC336Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Barrier To Autointegration Factor 1 (BANF1) - RPC336Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

BANF1 (transcript variant 1) - TP303270 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human BANF1 protein, His-tagged - BANF1-25H from Creative Biomart Category Protein Source E.coli Species Human

BANF1 Recombinant Protein Antigen - NBP2-38442PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BANF1 Peptide, Human - M34GP01318H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Barrier To Autointegration Factor 1 (BANF1) - RPU51306 from Biomatik Category Protein Prices $169.00, $347.00, $530.00, $662.20 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

BANF1 Recombinant Protein (OPCD01587) - OPCD01587 from Aviva Systems Biology Category Protein Source E.coli Species Human

Barrier To Autointegration Factor 1, Recombinant Protein - MBS2033508 from MyBioSource Category Protein Prices $170.00, $350.00, $540.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

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