Gene Symbol | LIFR |
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Entrez Gene | 3977 |
Alt Symbol | CD118, LIF-R, SJS2, STWS, SWS |
Species | Human |
Gene Type | protein-coding |
Description | leukemia inhibitory factor receptor alpha |
Other Description | CD118 antigen|LIF receptor|leukemia inhibitory factor receptor |
Swissprots | Q6LCD9 P42702 |
Accessions | EAW55972 P42702 AK290059 BAF82748 AK308158 AK309882 BC141428 AAI41429 BC153096 AAI53097 BP219669 BQ008945 BX648635 DA835819 DA857408 U66563 AAB61897 X61615 CAA43805 XM_011514040 XP_011512342 XM_011514041 XP_011512343 XM_011514042 XP_011512344 NM_001127671 NP_001121143 NM_002310 NP_002301 |
Function | Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Active human LIFR protein fragment - ab155609 from Abcam
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Human LIFR protein fragment - ab114580 from Abcam
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LIFR peptide - ab130816 from Abcam
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LIF R alpha Partial Recombinant Protein - H00003977-Q01 from Novus Biologicals
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LIF R alpha Recombinant Protein - H00003977-G01 from Novus Biologicals
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LIF R alpha Recombinant Protein - P3681 from Novus Biologicals
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Recombinant Human LIF R alpha, CF - 249-LR-050/CF from R&D Systems
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Recombinant Human LIF R alpha (Mammalian-expressed), CF - 7487-LR-050 from R&D Systems
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Human CD118 protein - orb83198 from Biorbyt
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Human LIFR Protein - abx067772 from Abbexa
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Human LIFR Protein - abx067767 from Abbexa
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Human LIFR Protein - abx067766 from Abbexa
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LIFR / CD118 - H00003977-G01 from Acris Antibodies
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LIFR / CD118 - H00003977-Q01-10 from Acris Antibodies
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LIFR / CD118 - H00003977-Q01-25 from Acris Antibodies
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LIFR / CD118 - P3681 from Acris Antibodies
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Leukemia Inhibitory Factor Receptor (LIFR), Human - 20-6805 from ARP American Research Products
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Leukemia Inhibitory Factor Receptor (LIFR), Human - 20-6806 from ARP American Research Products
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Leukemia Inhibitory Factor Receptor (LIFR), Human - 20-6807 from ARP American Research Products
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LIFR Recombinant Protein - 96-522 from ProSci
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LIFR fusion protein - ag18742 from Proteintech Group
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LIFR fusion protein - ag18886 from Proteintech Group
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Recombinant Human LIFR, His tagged - LIFR-611H from Creative Biomart
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Recombinant Human LIFR - LIFR-28855TH from Creative Biomart
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Recombinant Human LIFR - LIFR-687H from Creative Biomart
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