TELO2

Gene Symbol	TELO2
Entrez Gene	9894
Alt Symbol	CLK2, TEL2
Species	Human
Gene Type	protein-coding
Description	telomere maintenance 2
Other Description	TEL2, telomere maintenance 2, homolog|protein clk-2 homolog|telomere length regulation protein TEL2 homolog
Swissprots	Q9BR21 D3DU73 O75168 Q7LDV4 Q9Y4R8
Accessions	AAK61284 EAW85647 EAW85648 EAW85649 EAW85650 EAW85651 Q9Y4R8 AB014583 BAA31658 AK001786 BAG50974 AK302103 BAG63484 AL080126 CAB45724 AL137394 CAB70722 BC017188 AAH17188 BC028332 BQ446656 DB494123 XM_006720993 XP_006721056 XM_011522773 XP_011521075 XM_011522774 XP_011521076 XM_011522775 XP_011521077 XM_011522776 XP_011521078 XM_011522777 XP_011521079 XM_011522778 XP_011521080 XR_932982 XR_932983 NM_016111 NP_057195
Function	Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation. {ECO:0000269|PubMed:12670948, ECO:0000269|PubMed:20810650}.
Subcellular Location	Cytoplasm. Membrane. Nucleus. Chromosome, telomere {ECO:0000305}.
Top Pathways	Fanconi anemia pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CLK2 Antibody Blocking Peptide - LS-E3435 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLK2 Antibody Blocking Peptide - LS-E4422 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CLK2 Antibody Blocking Peptide - LS-E9029 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TELO2 Antibody Blocking Peptide - LS-E7602 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CLK2 Protein - H00001196-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human CLK2 Protein - H00001196-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CLK2 Peptide - P2536 from Novus Biologicals Category Peptide Species Human

TELO2-Antibody-C-term-Blocking-Peptide - BP4808b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CLK2 Blocking Peptide - abx062438 from Abbexa Category Peptide Species Human, Monkey

TELO2 fusion protein - Ag8763 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TELO2 fusion protein - Ag8834 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human TELO2, GST-tagged - TELO2-3180H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Telomere length regulation protein TEL2 homolog(TELO2) ,partia - CSB-YP897494HU CSB-EP897494HU CSB-BP897494HU CSB-MP897494HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TEL2, telomere maintenance 2, homolog (S. cerevisiae) (TELO2) - TP300291 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Telomere length regulation protein TEL2 homolog (TELO2), partial, Recombinant Protein - MBS1407341 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TEL2 Recombinant Protein Antigen - NBP1-81762PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TEL2 Protein - NBP1-81761PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

CLK2 Recombinant Protein Antigen - NBP2-47506PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CLK2 Peptide, Human - M34GP03293H from Creative Peptides Category Peptide Source Synthetic. Species Human

TELO2 Peptide, Human - M34GP15788H from Creative Peptides Category Peptide Source Synthetic. Species Human

CLK2 Recombinant Protein Antigen - NBP2-56937PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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