SLC9A3R2

Gene Symbol SLC9A3R2
Entrez Gene 9351
Alt Symbol E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1
Species Human
Gene Type protein-coding
Description solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Other Description NHE3 kinase A regulatory protein E3KARP|NHE3 regulatory factor 2|Na(+)/H(+) exchange regulatory cofactor NHE-RF2|SRY-interacting protein 1|sodium/hydrogen exchanger 3 kinase A regulatory protein|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2|solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2|solute carrier family 9 isoform A3 regulatory factor 2|tyrosine kinase activator protein 1
Swissprots O00556 D3DU84 Q15599 H3BSV6 D3DU85 Q3KQY7 O00272
Accessions AAC34208 BAA32696 BAA33216 EAW85563 EAW85564 EAW85565 EAW85566 Q15599 AF004900 AAC63061 AF035771 AAC52090 BC014513 AAH14513 BC069014 AAH69014 BC106001 AAI06002 BQ447156 BQ687174 BX377861 CB961565 DB495688 U82108 AAB53042 Z50150 CAA90511 XM_005255702 XP_005255759 XM_005255703 XP_005255760 XM_006720981 XP_006721044 NM_001130012 NP_001123484 NM_001252073 NP_001239002 NM_001252075 NP_001239004 NM_001252076 NP_001239005 NM_004785 NP_004776
Function Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. {ECO:0000269|PubMed:10455146, ECO:0000269|PubMed:9096337}.
Subcellular Location Endomembrane system {ECO:0000269|PubMed:9054412}; Peripheral membrane protein {ECO:0000269|PubMed:9054412}. Nucleus {ECO:0000269|PubMed:9054412}. Apical cell membrane {ECO:0000250}. Note=Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern. {ECO:0000250}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:9054412, ECO:0000269|PubMed:9096337}.
Top Pathways Aldosterone-regulated sodium reabsorption

NHERF2 (D3A5) Rabbit mAb - 9568 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3A5
Western blot analysis of extracts from MCF7 and T-47D cells using NHERF2 (D3A5) Rabbit mAb.

NHERF-2 (C-2) - sc-365388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
NHERF-2 (C-2): sc-365388. Western blot analysis of NHERF-2 expression in NIH/3T3 whole cell lysate.

NHERF-2 (G-21) - sc-21115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NHERF-2 (C-14) - sc-21117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NHERF-2 (C-14): sc-21117. Western blot analysis of NHERF-2 expression in RAW 264.7 (A) and NIH/3T3 (B) whole cell lysates.

NHERF-2 (H-16) - sc-21116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NHERF-2 (H-90) - sc-33615 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-SLC9A3R2 antibody - ab40825 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-SLC9A3R2 antibody (ab40825) at 0.3 µg/ml + Human Kidney lysate at 35 µgdeveloped using the ECL technique

Anti-SLC9A3R2 antibody [32B6] - ab151443 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 32B6
Anti-SLC9A3R2 antibody [32B6] (ab151443) at 1/100 dilution + HaCat Human keratinocyte cells

Anti-SLC9A3R2 / SIP1 Antibody (aa276-290) - LS-C55175 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLC9A3R2 / SIP1 Antibody (Internal) - LS-C145101 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC9A3R2 / SIP1 Antibody (aa321-331) - LS-C55477 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.3 ug/ml) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SLC9A3R2 / SIP1 Antibody (N-Terminus) - LS-C135148 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SLC9A3R2 / SIP1 antibody Western Blot of Rat Brain.

Anti-SLC9A3R2 / SIP1 Antibody (aa124-173) - LS-C146202 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SLC9A3R2 antibody LS-C146202 Western blot of Mouse Liver lysate. Antibody concentration 1 ug/ml.

Anti-SLC9A3R2 / SIP1 Antibody (aa56-337) - LS-C314866 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SLC9A3R2 / SIP1.

Anti-SLC9A3R2 / SIP1 Antibody (aa56-326) - LS-C314868 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant SLC9A3R2 / SIP1.

Anti-SLC9A3R2 / SIP1 Antibody (aa82-307) - LS-C185404 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (50 ug of whole cell lysate). A: mouse liver. 15% SDS PAGE. SLC9A3R2 / SIP-1 antibody diluted at 1:1000.

NHERF-2 Antibody - NBP1-84944 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: NHERF-2 Antibody [NBP1-84944] - Staining of human cell line U-251MG shows positivity in plasma membrane.

NHERF-2 Antibody - NB100-2450 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: NHERF-2 Antibody [NB100-2450] - (0.3ug/ml) Analysis of human kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

NHERF-2 Antibody - NBP1-31804 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NHERF-2 Antibody [NBP1-31804] - NHERF-2 antibody detects NHERF-2 protein by western blot analysis. Whole cell extracts (30 ug) was separated by 10 % SDS-PAGE, and blotted with NHERF-2 antibody diluted by 1:1000

Anti-SLC9A3R2 Isoform A3 antibody produced in goat - SAB2500952 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC9A3R2 (isoform A3): <B>Cat. No. SAB2500952</B>: (3 μg/mL) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

Anti-SLC9A3R2 antibody produced in goat - SAB2501927 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC9A3R2<B>Cat. No. SAB2501927</B>: Immunoblotting (1 μg/mL) staining of Daudi lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-SLC9A3R2 antibody produced in rabbit - HPA001672 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC9A3R2: <B>Cat. No. HPA001672</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing strong membranous and/or cytoplasmic staining of cells in glomeruli as well as positively stained endothelial cells.

NHERF2-isoform-b-e-Antibody-internal-region - AF2461a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2461a (1 µg/ml) staining of Daudi lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

NHERF2-isoform-a-Antibody - AF1731a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1731a (3 µg/ml) staining of paraffin embedded Human Kidney. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining.

NHERF2 (isoform a) antibody, Internal - GTX89452 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-NHERF2 (isoform a) antibody, Internal used in IHC (Formalin-fixed paraffin-embedded sections). GTX89452
Search more