SLC9A3R2

Gene Symbol	SLC9A3R2
Entrez Gene	9351
Alt Symbol	E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1
Species	Human
Gene Type	protein-coding
Description	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Other Description	NHE3 kinase A regulatory protein E3KARP|NHE3 regulatory factor 2|Na(+)/H(+) exchange regulatory cofactor NHE-RF2|SRY-interacting protein 1|sodium/hydrogen exchanger 3 kinase A regulatory protein|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2|solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2|solute carrier family 9 isoform A3 regulatory factor 2|tyrosine kinase activator protein 1
Swissprots	O00556 D3DU84 Q15599 H3BSV6 D3DU85 Q3KQY7 O00272
Accessions	AAC34208 BAA32696 BAA33216 EAW85563 EAW85564 EAW85565 EAW85566 Q15599 AF004900 AAC63061 AF035771 AAC52090 BC014513 AAH14513 BC069014 AAH69014 BC106001 AAI06002 BQ447156 BQ687174 BX377861 CB961565 DB495688 U82108 AAB53042 Z50150 CAA90511 XM_005255702 XP_005255759 XM_005255703 XP_005255760 XM_006720981 XP_006721044 NM_001130012 NP_001123484 NM_001252073 NP_001239002 NM_001252075 NP_001239004 NM_001252076 NP_001239005 NM_004785 NP_004776
Function	Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus. {ECO:0000269|PubMed:10455146, ECO:0000269|PubMed:9096337}.
Subcellular Location	Endomembrane system {ECO:0000269|PubMed:9054412}; Peripheral membrane protein {ECO:0000269|PubMed:9054412}. Nucleus {ECO:0000269|PubMed:9054412}. Apical cell membrane {ECO:0000250}. Note=Localizes with EZR and PODXL at the apical cell membrane of glomerular epithelium cells and the sides of the food processes (By similarity). Nuclear, in a punctate pattern. {ECO:0000250}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:9054412, ECO:0000269|PubMed:9096337}.
Top Pathways	Aldosterone-regulated sodium reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SLC9A3R2 peptide (286-296) - ab45828 from Abcam Category Peptide Species Human

SIP1 Antibody Blocking Peptide - LS-E14665 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIP1 Antibody Blocking Peptide - LS-E14666 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SIP1 Antibody Blocking Peptide - LS-E30953 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC9A3R2 / SIP1 Antibody Blocking Peptide - LS-E16136 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC9A3R2 / SIP1 Antibody Blocking Peptide - LS-E16137 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC9A3R2 / SIP1 Antibody Blocking Peptide - LS-E25969 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC9A3R2 / SIP1 Antibody Blocking Peptide - LS-E25970 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC9A3R2-Antibody-Center-Blocking-Peptide - BP18832c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NHERF2 (isoform a) blocking peptide - GTX89452-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

NHERF2 (isoform b) blocking peptide - GTX89484-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

SLC9A3R2 Immunizing peptide - orb15256 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Sip1 Blocking Peptide - 33R-7344 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SIP1 Blocking Peptide - 33R-3856 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Slc9a3r2 Blocking Peptide - 33R-8058 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC9A3R2 Peptide - AC21-0796-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

SLC9A3R2 Peptide - AC21-0797-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

NHERF2 Peptide - 45-967P from ProSci Category Peptide Species Human

SLC9A3R2 Peptide - 46-379P from ProSci Category Peptide Species Human

SLC9A3R2 fusion protein - Ag13476 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human SLC9A3R2, GST-tagged - SLC9A3R2-2789H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Tyrosine Kinase Activator Protein 1 (TKA1) - RPB976Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Tyrosine Kinase Activator Protein 1 (TKA1) - RPB976Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Tyrosine Kinase Activator Protein 1 (TKA1) - RPB976Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Tyrosine Kinase Activator Protein 1 (TKA1) - RPB976Hu02 from Cloud-clone Category Protein Source E.coli Species Human

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