FIGN

Gene Symbol FIGN
Entrez Gene 55137
Alt Symbol -
Species Human
Gene Type protein-coding
Description fidgetin
Other Description -
Swissprots B3KWM0 Q9NVZ9 Q5HY92 Q9H6M5
Accessions AAX81992 CAK32384 EAX11345 Q5HY92 AK001267 BAA91590 AK025747 BAB15231 AK125324 BAG54182 BC148649 AAI48650 BC156958 AAI56959 BX649105 CAI45980 EU832143 ACE87493 EU832236 ACE86806 XM_005246661 XP_005246718 XM_005246662 XP_005246719 XM_011511389 XP_011509691 XM_011511390 XP_011509692 XM_011511391 XP_011509693 NM_018086 NP_060556
Function ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. {ECO:0000269|PubMed:22672901}.
Subcellular Location Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22672901}. Note=Localizes to centrosomes throughout mitosis and to the spindle midzone during telophase.

fidgetin (H-146) - sc-68343 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
fidgetin (H-146): sc-68343. Western blot analysis of fidgetin expression in mouse heart tissue extract.

fidgetin (N-20) - sc-54888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
fidgetin (N-20): sc-54888. Western blot analysis of human recombinant fidgetin fusion protein.

fidgetin (Y-16) - sc-54890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FIGN antibody - ab129906 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FIGN antibody (ab129906) at 1/100 dilution + Mouse kidney tissue lysate at 35 µg

Anti-FIGN antibody - ab122238 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent staining of Human cell line U-2 OS shows positivity in plasma membrane and cytoplasm. Recommended concentration of ab122238 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Anti-FIGN / Fidgetin Antibody (aa615-643) - LS-C166157 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FIGN Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The FIGN antibody detected the FIGN protein (arrow).

Anti-FIGN / Fidgetin Antibody (aa615-643, AP) - LS-C235311 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody (aa615-643, APC) - LS-C235312 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody (aa615-643, Biotin) - LS-C235313 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody - LS-C190076 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody (aa615-643, Azide-free, HRP) - LS-C248994 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody (aa615-643, FITC) - LS-C235314 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody (aa615-643, PE) - LS-C235315 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FIGN / Fidgetin Antibody (aa614-643) - LS-C321392 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

FIGN Antibody - NBP1-86313 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: FIGN Antibody [NBP1-86313] - Staining of human corpus, uterine shows strong nuclear and cytoplasmic positivity in glandular cells.

FIGN Antibody (2F8) - H00055137-M02-100ug from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8

Monoclonal Anti-FIGN antibody produced in mouse - SAB1412847 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2F8
<B>Immunoblotting</B><BR/>Anti-FIGN:<B>Cat. No. SAB1412847</B>: Antibody concentration: 1–5 μg/mL. Immunofluorescence band of ~83 kDa using HeLa lysate.

ANTI-FIGN (C-TERM) antibody produced in rabbit - SAB1304554 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FIGN antibody produced in rabbit - HPA034987 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-FIGN: <B>Cat. No. HPA034987</B>: Immunohistochemical staining of human corpus, uterine shows strong nuclear and cytoplasmic positivity in glandular cells.

FIGN-Antibody-C-term - AP16768b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
FIGN Antibody (C-term) (Cat. #AP16768b) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the FIGN antibody detected the FIGN protein (arrow).

FIGN Antibody - C-terminal region (OAAB12183) - OAAB12183 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

Anti -FIGN, CT (FIGN, Fidgetin) - 035657 from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -FIGN, CT (FIGN, Fidgetin) (AP) - 035657-AP from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -FIGN, CT (FIGN, Fidgetin) (APC) - 035657-APC from USBiological Life Science

Host Rabbit
Clonality Polyclonal

Anti -FIGN, CT (FIGN, Fidgetin) (Azide free) (HRP) - 035657-HRP from USBiological Life Science

Host Rabbit
Clonality Polyclonal
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