FIGN

Gene Symbol	FIGN
Entrez Gene	55137
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	fidgetin
Other Description	-
Swissprots	B3KWM0 Q9NVZ9 Q5HY92 Q9H6M5
Accessions	AAX81992 CAK32384 EAX11345 Q5HY92 AK001267 BAA91590 AK025747 BAB15231 AK125324 BAG54182 BC148649 AAI48650 BC156958 AAI56959 BX649105 CAI45980 EU832143 ACE87493 EU832236 ACE86806 XM_005246661 XP_005246718 XM_005246662 XP_005246719 XM_011511389 XP_011509691 XM_011511390 XP_011509692 XM_011511391 XP_011509693 NM_018086 NP_060556
Function	ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. {ECO:0000269|PubMed:22672901}.
Subcellular Location	Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22672901}. Note=Localizes to centrosomes throughout mitosis and to the spindle midzone during telophase.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FIGN protein fragment - ab162976 from Abcam Category Protein Source Wheat germ Species Human

FIGN / Fidgetin Antibody Blocking Peptide - LS-E4453 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human FIGN Protein - H00055137-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FIGN-Antibody-C-term-Blocking-Peptide - BP16768b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Fidgetin - H00055137-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Fidgetin - H00055137-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Recombinant Fidgetin (FIGN) - RPJ106Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Fidgetin (FIGN) - RPJ106Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Fidgetin(FIGN) - CSB-YP008676HU CSB-EP008676HU CSB-BP008676HU CSB-MP008676HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Fidgetin Protein (Recombinant) - abx166983 from Abbexa Category Protein Source Human Species Human

FIGN Recombinant Protein Antigen - NBP1-86313PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

FIGN Peptide, Human - M34GP05747H from Creative Peptides Category Peptide Source Synthetic. Species Human

Fidgetin, Recombinant Protein - MBS2030906 from MyBioSource Category Protein Prices $190.00, $395.00, $610.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Fidgetin (FIGN), Recombinant Protein - MBS1419642 from MyBioSource Category Protein Prices $1,575.00, $1,575.00, $1,800.00, $1,800.00, $2,715.00, $2,715.00, $3,155.00, $3,155.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Recombinant Fidgetin (FIGN) - RPU53249 from Biomatik Category Protein Prices $194.00, $396.00, $605.00, $721.60 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

FIGN Recombinant Protein (OPCD03237) - OPCD03237 from Aviva Systems Biology Category Protein Source E.coli Species Human

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