FIGN

Gene Symbol FIGN
Entrez Gene 55137
Alt Symbol -
Species Human
Gene Type protein-coding
Description fidgetin
Other Description -
Swissprots B3KWM0 Q9NVZ9 Q5HY92 Q9H6M5
Accessions AAX81992 CAK32384 EAX11345 Q5HY92 AK001267 BAA91590 AK025747 BAB15231 AK125324 BAG54182 BC148649 AAI48650 BC156958 AAI56959 BX649105 CAI45980 EU832143 ACE87493 EU832236 ACE86806 XM_005246661 XP_005246718 XM_005246662 XP_005246719 XM_011511389 XP_011509691 XM_011511390 XP_011509692 XM_011511391 XP_011509693 NM_018086 NP_060556
Function ATP-dependent microtubule severing protein. Severs microtubules along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtubule growth from and attachment to centrosomes. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. {ECO:0000269|PubMed:22672901}.
Subcellular Location Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22672901}. Note=Localizes to centrosomes throughout mitosis and to the spindle midzone during telophase.

fidgetin CRISPR/Cas9 KO Plasmid (h) - sc-404648 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin HDR Plasmid (h) - sc-404648-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin Double Nickase Plasmid (h) - sc-404648-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin Double Nickase Plasmid (h2) - sc-404648-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin CRISPR Activation Plasmid (h) - sc-404648-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin CRISPR Activation Plasmid (h2) - sc-404648-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin Lentiviral Activation Particles (h) - sc-404648-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin Lentiviral Activation Particles (h2) - sc-404648-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

fidgetin siRNA (h) - sc-62318 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

fidgetin shRNA Plasmid (h) - sc-62318-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

fidgetin shRNA (h) Lentiviral Particles - sc-62318-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU009041 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN8695 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8695 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13207 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13207

FIGN siRNA (Human) - CRJ0495 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FIGN RNAi - H00055137-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

FIGN - MBS829746 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FIGN (NM_018086.2) - SHH295021 from Creative biogene

Category siRNA
Species Reactivities Human

Human FIGN siRNA - orb270996 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FIGN shRNA Plasmid (Human) - CHJ0495 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FIGN miRNA 3'UTR clone - MiUTR1H-03657 from Creative biogene

Species Reactivities Human
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