PPAPDC2

Gene Symbol	PPAPDC2
Entrez Gene	403313
Alt Symbol	PDP1, PSDP, bA6J24.6
Species	Human
Gene Type	protein-coding
Description	phosphatidic acid phosphatase type 2 domain containing 2
Other Description	PPAP2 domain-containing protein 2|phosphatidic acid phosphatase type 2 domain-containing protein 2|polyisoprenoid diphosphate phosphatase type 1|presqualene diphosphate phosphatase
Swissprots	Q5JVJ6 Q8IY26 B3KY05 Q8NCK9
Accessions	EAW58785 Q8IY26 AK074672 AK128369 BAG54667 AK296773 BAG59352 BC036833 BC038108 AAH38108 BU632000 DA416947 NM_203453 NP_982278
Function	Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. {ECO:0000269|PubMed:16464866}.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain. {ECO:0000269|PubMed:16464866}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDP1 Antibody Blocking Peptide - LS-E1686 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPAPDC2 Antibody Blocking Peptide - LS-E5204 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPAPDC2 Antibody Blocking Peptide - LS-E30825 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PPAPDC2 Antibody Blocking Peptide - LS-E20265 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PPAPDC2 Antibody Blocking Peptide - LS-E20266 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDP1/PPAPDC2 Peptide - NBP1-76245PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

PPAPDC2-Antibody-N-term-Blocking-Peptide - BP17641a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PPAPDC2 Peptide - GTX85222-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

PPAPDC2 Blocking Peptide - 33R-6306 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PPAPDC2 Blocking Peptide - 33R-3021 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PPAPDC2 Control Peptide - AP30688CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

PPAPDC2 Peptide - 5517P from ProSci Category Peptide Species Human

PDP1/PPAPDC2 Recombinant Protein Antigen - NBP1-83443PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PPAPDC2 Peptide, Human - M34GP12169H from Creative Peptides Category Peptide Source Synthetic. Species Human

PPAPDC2 fusion protein - Ag23856 from Proteintech Group Category Protein Species Human

Presqualene diphosphate phosphatase (PPAPDC2), Recombinant Protein - MBS7026889 from MyBioSource Category Protein Prices $1,105.00, $2,090.00, $3,300.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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