PPAPDC2

Gene Symbol PPAPDC2
Entrez Gene 403313
Alt Symbol PDP1, PSDP, bA6J24.6
Species Human
Gene Type protein-coding
Description phosphatidic acid phosphatase type 2 domain containing 2
Other Description PPAP2 domain-containing protein 2|phosphatidic acid phosphatase type 2 domain-containing protein 2|polyisoprenoid diphosphate phosphatase type 1|presqualene diphosphate phosphatase
Swissprots Q5JVJ6 Q8IY26 B3KY05 Q8NCK9
Accessions EAW58785 Q8IY26 AK074672 AK128369 BAG54667 AK296773 BAG59352 BC036833 BC038108 AAH38108 BU632000 DA416947 NM_203453 NP_982278
Function Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. {ECO:0000269|PubMed:16464866}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Widely expressed. Expressed in most organs, in particular gastrointestinal organs, spleen, placenta, kidney, thymus and brain. {ECO:0000269|PubMed:16464866}.

PPAPDC2 CRISPR/Cas9 KO Plasmid (h) - sc-416001 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 HDR Plasmid (h) - sc-416001-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 Double Nickase Plasmid (h) - sc-416001-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 Double Nickase Plasmid (h2) - sc-416001-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 CRISPR Activation Plasmid (h) - sc-416001-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 CRISPR Activation Plasmid (h2) - sc-416001-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 Lentiviral Activation Particles (h) - sc-416001-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 Lentiviral Activation Particles (h2) - sc-416001-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PPAPDC2 siRNA (h) - sc-92762 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPAPDC2 shRNA Plasmid (h) - sc-92762-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PPAPDC2 shRNA (h) Lentiviral Particles - sc-92762-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU217311 from Sigma-Aldrich

Category siRNA
Prices $140.00
Sizes 50 µg

MISSION® Human Phosphatase - SIHP0453 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0452 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

MISSION® Human Phosphatase - SIHP0451 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 250 pmol

CompoZr® Knockout ZFN Kit - CKOZFN17201 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17201 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10800 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10800

PPAPDC2 siRNA (Human) - CRJ8177 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PPAPDC2 (NM_203453.3) - SHH380300 from Creative biogene

Category siRNA
Species Reactivities Human

Human PPAPDC2 siRNA - orb278678 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PPAPDC2 shRNA Plasmid (Human) - CHJ8177 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PPAPDC2 miRNA 3'UTR clone - MiUTR4H-TG06914 from Creative biogene

Species Reactivities Human
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