NKX3-1

Gene Symbol NKX3-1
Entrez Gene 4824
Alt Symbol BAPX2, NKX3, NKX3.1, NKX3A
Species Human
Gene Type protein-coding
Description NK3 homeobox 1
Other Description NK homeobox, family 3, A|NK3 transcription factor homolog A|NK3 transcription factor related, locus 1|homeobox protein NK-3 homolog A|homeobox protein Nkx-3.1
Swissprots Q9H2P4 Q9H2P7 Q9H2P6 Q9H2P5 Q9HBG0 O15465 Q99801
Accessions EAW63613 Q99801 AF247704 AAG09781 AF249669 AAG39735 AF249670 AAG39736 AF249671 AAG39737 AF249672 AAG39738 BC074863 AAH74863 BC074864 AAH74864 BC111569 BC111574 BF511129 EU446642 ABZ92171 U80669 AAB38747 U91540 AAB68662 NM_001256339 NP_001243268 NM_006167 NP_006158 NR_046072
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. {ECO:0000269|PubMed:19462257}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:11137288}.
Tissue Specificity Highly expressed in the prostate and, at a lower level, in the testis. {ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}.
Top Pathways Prostate cancer

Human Nkx3.1 full length protein - ab139222 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of 3 µg ab139222.

Human Nkx3.1 full length protein - ab134861 from Abcam

Category Protein
Source E. coli
Species Human

Human Nkx3.1 protein fragment - ab114523 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114523 at approximately 37.73kDa stained with Coomassie Blue.

NKX3-1 Antibody Blocking Peptide - LS-E4805 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NKX3-1 Antibody Blocking Peptide - LS-E11200 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NKX3-1 Antibody Blocking Peptide - LS-E13951 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NKX3-1 Antibody Blocking Peptide - LS-E13318 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NKX3-1 Antibody Blocking Peptide - LS-E6543 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NKX3-1 Antibody Blocking Peptide - LS-E9892 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

NKX3.1 Partial Recombinant Protein - H00004824-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human NKX3.1 Protein - NBP2-23290 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Source E.coli
Species Human

NKX3-1-Antibody-C-term-Blocking-Peptide - BP17186b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

NKX3-1-Antibody-Center-Blocking-Peptide - BP8996c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human NKX3-1 protein - orb191094 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Species Human

NKX3-1 protein (His tag) - 30R-2946 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

NKX3-1 Blocking Peptide - abx063007 from Abbexa

Category Peptide
Species Human

NKX3-1 (1-234, His-tag) - AR50706PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
NKX3-1

NKX3-1 (1-234, His-tag) - AR50706PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
NKX3-1

NKX3-1 - H00004824-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

NKX3-1 - H00004824-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

NKX3-1, 1-234aa, Human, His tag, E.coli - 01-P1882 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

NKX3-1 fusion protein - Ag17305 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

NKX3-1 fusion protein - ag4070 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

NKX3-1 fusion protein - Ag14496 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

NKX3-1 fusion protein - Ag17640 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human
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