NKX3-1

Gene Symbol NKX3-1
Entrez Gene 4824
Alt Symbol BAPX2, NKX3, NKX3.1, NKX3A
Species Human
Gene Type protein-coding
Description NK3 homeobox 1
Other Description NK homeobox, family 3, A|NK3 transcription factor homolog A|NK3 transcription factor related, locus 1|homeobox protein NK-3 homolog A|homeobox protein Nkx-3.1
Swissprots Q9H2P4 Q9H2P7 Q9H2P6 Q9H2P5 Q9HBG0 O15465 Q99801
Accessions EAW63613 Q99801 AF247704 AAG09781 AF249669 AAG39735 AF249670 AAG39736 AF249671 AAG39737 AF249672 AAG39738 BC074863 AAH74863 BC074864 AAH74864 BC111569 BC111574 BF511129 EU446642 ABZ92171 U80669 AAB38747 U91540 AAB68662 NM_001256339 NP_001243268 NM_006167 NP_006158 NR_046072
Function Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. {ECO:0000269|PubMed:19462257}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:11137288}.
Tissue Specificity Highly expressed in the prostate and, at a lower level, in the testis. {ECO:0000269|PubMed:9226374, ECO:0000269|PubMed:9537602}.
Top Pathways Prostate cancer

Nkx-3.1 CRISPR/Cas9 KO Plasmid (h) - sc-401789 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 HDR Plasmid (h) - sc-401789-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 Double Nickase Plasmid (h) - sc-401789-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 Double Nickase Plasmid (h2) - sc-401789-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 CRISPR Activation Plasmid (h) - sc-401789-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 CRISPR Activation Plasmid (h2) - sc-401789-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 Lentiviral Activation Particles (h) - sc-401789-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 Lentiviral Activation Particles (h2) - sc-401789-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Nkx-3.1 siRNA (h) - sc-36077 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nkx-3.1 shRNA Plasmid (h) - sc-36077-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Nkx-3.1 shRNA (h) Lentiviral Particles - sc-36077-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU089291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15336 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15336 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11560 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11560

NKX3-1 siRNA (Human) - CRH3202 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NKX3.1 RNAi - H00004824-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Human NKX3-1 siRNA - orb263704 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NKX3-1 shRNA Plasmid (Human) - CHH3202 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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