DCAF7

Gene Symbol DCAF7
Entrez Gene 10238
Alt Symbol AN11, HAN11, SWAN-1, WDR68
Species Human
Gene Type protein-coding
Description DDB1 and CUL4 associated factor 7
Other Description DDB1- and CUL4-associated factor 7|WD repeat-containing protein 68|WD repeat-containing protein An11 homolog|human anthocyanin|seven-WD-repeat protein of the AN11 family-1
Swissprots D3DU14 P61962 B4E039
Accessions EAW94305 EAW94306 P61962 AA206721 AA634196 AI580937 AK022145 AK025925 AK026008 AK130672 AK294925 BAG58007 AK303212 BAG64301 AL832440 BC001264 AAH01264 BC024682 BC027489 BE889428 BF058090 BF507629 BG684075 BG819062 BM272287 BM559804 BM673647 BQ221019 BQ435051 BX648608 CB162675 CD245570 DA230140 DQ891233 ABM82159 DQ894417 ABM85343 HY023965 U94747 AAC18913 NM_005828 NP_005819 NR_073585 NM_001003725
Function Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000250, ECO:0000269|PubMed:16887337, ECO:0000269|PubMed:16949367}.
Subcellular Location Cytoplasm. Nucleus. Note=Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.

WDR68 (S-15) - sc-160914 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

WDR68 (T-19) - sc-160915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-WDR68 antibody - ab170113 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-WDR68 antibody (ab170113) at 1/200 dilutionLane 1 : HeLa cell lysateLane 2 : 293T cell lysate

Anti-WDR68 antibody - ab130565 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-WDR68 antibody (ab130565) at 1/100 dilution + HepG2 cell line lysate at 35 µg

Anti-WDR68 antibody - ab70148 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-WDR68 antibody (ab70148) at 1/500 dilutionLane 1 : WDR68 transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-WDR68 antibody [EPR8712] - ab138490 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8712
Overlay histogram showing HeLa cells stained with ab138490 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab138490, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-DCAF7 / WDR68 Antibody (aa285-314, AP) - LS-C218438 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (aa285-314, APC) - LS-C218439 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (aa285-314, Biotin) - LS-C218440 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (aa285-314, FITC) - LS-C218441 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (aa285-314, Azide-free, HRP) - LS-C218442 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (aa285-314, PE) - LS-C218443 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (aa285-314) - LS-C326345 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-DCAF7 / WDR68 Antibody (N-Terminus) - LS-C135268 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DCAF7 / WDR68 antibody LS-C135268 Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml.

Anti-DCAF7 / WDR68 Antibody (N-Terminus) - LS-C345102 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of DCAF7 Antibody with human Gallbladder Tumor lysate.

Anti-DCAF7 / WDR68 Antibody - LS-C334947 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of 293T cell line, using DCAF7 antibody.

Anti-DCAF7 / WDR68 Antibody (aa285-314) - LS-C157370 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
WDR68 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The WDR68 antibody detected the WDR68 protein (arrow).

WDR68 Antibody - NBP1-92589 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WDR68 Antibody - NBP1-92590 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WDR68 Antibody [NBP1-92590] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

WDR68 Antibody - H00010238-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: WDR68 Antibody [H00010238-B01P] - Analysis of WDR68 expression in transfected 293T cell line by WDR68 polyclonal antibody. Lane 1: WDR68 transfected lysate(37.62 KDa). Lane 2: Non-transfected lysate.

WDR68 Antibody - H00010238-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

WDR68 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13682R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WDR68 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13682R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WDR68 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13682R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WDR68 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13682R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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