ZFP36L2

Gene Symbol	ZFP36L2
Entrez Gene	678
Alt Symbol	BRF2, ERF-2, ERF2, RNF162C, TIS11D
Species	Human
Gene Type	protein-coding
Description	ZFP36 ring finger protein-like 2
Other Description	EGF-response factor 2|ZFP36-like 2|butyrate response factor 2|zinc finger protein 36, C3H type-like 1|zinc finger protein 36, C3H type-like 2|zinc finger protein 36, C3H1 type-like 2|zinc finger protein, C3H type, 36-like 2
Swissprots	Q9BSJ3 Q53TB4 P47974
Accessions	AAA91778 AAY14992 EAX00305 EAX00306 P47974 BC005010 AAH05010 BC020369 BE222042 BI489986 BI548620 DQ893399 ABM84325 DQ896782 ABM87781 N67537 X78992 CAA55592 NM_006887 NP_008818
Function	mRNA-binding protein that plays a key role in self- renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit- erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation (By similarity). {ECO:0000250, ECO:0000269|PubMed:14981510}.
Subcellular Location	Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TIS11D full length protein - ab152243 from Abcam Category Protein Source Wheat germ Species Human

ZFP36L2 Antibody Blocking Peptide - LS-E5227 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZFP36L2 Blocking Peptide - LS-E11780 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TIS11D Recombinant Protein - H00000678-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

ZFP36L2-Antibody-Center-Blocking-Peptide - BP17671c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZFP36L2 - H00000678-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

ZFP36L2 - H00055290-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

ZFP36L2 fusion protein - ag13515 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ZFP36L2 fusion protein - Ag13518 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TIS11D (H243) Peptide - BS2278P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Zinc finger protein 36, C3H1 type-like 2(ZFP36L2) - CSB-YP026450HU CSB-EP026450HU CSB-BP026450HU CSB-MP026450HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Zinc finger protein 36, C3H1 type-like 2(ZFP36L2) , Recombinant Protein - MBS955463 from MyBioSource Category Protein Prices $2,100.00, $2,100.00, $2,560.00, $2,560.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TIS11D Recombinant Protein Antigen - NBP1-92510PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZFP36L2 Blocking Peptide - abx061059 from Abbexa Category Peptide Species Human, Mouse, Bovine

ZFP36L2 Peptide, Human - M34GP17794H from Creative Peptides Category Peptide Source Synthetic. Species Human

ZFP36L2 Blocking Peptide - CBP4972 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Bovine

ZFP36L2 peptide - orb319118 from Biorbyt Category Peptide

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