ZFP36L2

Gene Symbol ZFP36L2
Entrez Gene 678
Alt Symbol BRF2, ERF-2, ERF2, RNF162C, TIS11D
Species Human
Gene Type protein-coding
Description ZFP36 ring finger protein-like 2
Other Description EGF-response factor 2|ZFP36-like 2|butyrate response factor 2|zinc finger protein 36, C3H type-like 1|zinc finger protein 36, C3H type-like 2|zinc finger protein 36, C3H1 type-like 2|zinc finger protein, C3H type, 36-like 2
Swissprots Q9BSJ3 Q53TB4 P47974
Accessions AAA91778 AAY14992 EAX00305 EAX00306 P47974 BC005010 AAH05010 BC020369 BE222042 BI489986 BI548620 DQ893399 ABM84325 DQ896782 ABM87781 N67537 X78992 CAA55592 NM_006887 NP_008818
Function mRNA-binding protein that plays a key role in self- renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit- erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation (By similarity). {ECO:0000250, ECO:0000269|PubMed:14981510}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.

TIS11D CRISPR/Cas9 KO Plasmid (h) - sc-405406 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D HDR Plasmid (h) - sc-405406-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D Double Nickase Plasmid (h) - sc-405406-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D Double Nickase Plasmid (h2) - sc-405406-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D CRISPR Activation Plasmid (h) - sc-405406-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D CRISPR Activation Plasmid (h2) - sc-405406-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D Lentiviral Activation Particles (h) - sc-405406-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D Lentiviral Activation Particles (h2) - sc-405406-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TIS11D siRNA (h) - sc-76674 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIS11D shRNA Plasmid (h) - sc-76674-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TIS11D shRNA (h) Lentiviral Particles - sc-76674-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN23183 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23183 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06292 from Sigma-Aldrich

Category miRNA

ZFP36L2 siRNA (Human) - CRH0472 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TIS11D RNAi - H00000678-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

ZFP36L2 - MBS8200076 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFP36L2(NM_006887.4) - SHG104861 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZFP36L2 siRNA - orb260974 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFP36L2 shRNA Plasmid (Human) - CHH0472 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFP36L2 miRNA 3'UTR clone - MiUTR1H-11431 from Creative biogene

Species Reactivities Human
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