PDCD6IP

Gene Symbol PDCD6IP
Entrez Gene 10015
Alt Symbol AIP1, ALIX, DRIP4, HP95
Species Human
Gene Type protein-coding
Description programmed cell death 6 interacting protein
Other Description ALG-2 interacting protein 1|ALG-2-interacting protein X|PDCD6-interacting protein|apoptosis-linked gene 2-interacting protein X|dopamine receptor interacting protein 4|programmed cell death 6-interacting protein
Swissprots E9PFU1 Q9P2H2 Q9NUN0 C5MQH7 Q9UKL5 Q9BX86 Q6NUS1 Q8WUM4
Accessions EAW64468 EAW64469 Q8WUM4 AB037796 BAA92613 AF151793 AAF08220 AF250394 AAQ14260 AF349951 AAK20398 AI346371 AK002122 BAA92092 AK295042 BAG58093 AK298727 BAH12857 AL695629 BC020066 AAH20066 BC068454 AAH68454 BI492166 BI562417 BM669193 BQ024882 BQ895877 BT007367 AAP36031 BU165197 BU194828 CR739098 DA149360 DA652213 GQ131806 ACS12984 XM_011533252 XP_011531554 XM_011533253 XP_011531555 NM_001162429 NP_001155901 NM_001256192 NP_001243121 NM_013374 NP_037506 NR_027867
Function Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cel
Subcellular Location Cytoplasm, cytosol. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Colocalized with CEP55 in the midbody during cytokinesis. Colocalized with CEP55 at centrosomes of non-dividing cells.
Top Pathways Endocytosis

Human PDCD6IP / ALIX ELISA Kit (Sandwich ELISA) - LS-F7886 from LifeSpan Bioscience

Category ELISA Kit
Prices $690.00
Sizes 1 plate
Sensitivity 0.313 ng/ml
Range 0.313-20 ng/ml

Human PDCD6IP ELISA Kit - abx152671 from Abbexa

Category ELISA Kit
Sensitivity 0.107 ng/ml
Range 0.313 ng/ml - 20 ng/ml

PDCD6IP (Human) IP-WB Antibody Pair - H00010015-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

PDCD6IP (Human) Matched Antibody Pair - H00010015-AP51 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

programmed cell death 6 interacting protein, ELISA Kit - MBS943605 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 11.7 pg/ml
Range 47 pg/ml-3000 pg/ml

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS065796 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS060942 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS100115 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS048670 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS087085 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS093495 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS079947 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS050764 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS070738 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/ml.
Range 0.5 ng/ml - 16 ng/ml.

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS066914 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS080514 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS053381 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS048530 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS054679 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS088734 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS051381 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS083905 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS085218 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS103918 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Programmed Cell Death Protein 6 Interacting Protein, ELISA Kit - MBS061680 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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